Description:

About the Job

The Bioprocess Development and Launch Department at the Bioresearch Center in Worcester MA is seeking a highly motivated molecular biologist to join the CHO Cell Line Development team and advance the Biologics pipeline.

The scientist in this position will

have several responsibilities in supporting CHO biologics pipeline including genetic characterization of cell lines and cell banks. A strong candidate will have in-depth experience with a variety of molecular biology techniques and mammalian cell culture/aseptic technique as well as exceptional attention to detail demonstrated skills and productivity in laboratory research and strong writing and communication skills.

Key Responsibilities:

Characterize CHO cell lines using molecular biology techniques including qPCR ddPCR Southern blot and northern blot

Sanger sequencing analysis

Design of primer/probe reagents for gene copy number analysis

Use of gel and blot imaging instruments

Maintain detailed accurate and clear documentation of experiments and activities

Effectively organize and communicate research progress and planned activities through oral and written presentations

Collaborate with colleagues in the Cell Line Development group and across multiple functional areas of the Bioprocess Development and Launch department to advance the company Biologics Pipeline

bull Maintain a high level of productivity in the lab

Demonstrate scientific initiative and creative thinking to achieve project goals and contribute team performance in a climate of scientific rigor

Contribute to the smooth and effective operation of the CHO Cell Line Development labs through the 5S program

Understand and adhere to corporate standards regarding code of conduct safety appropriate handling of materials and GxP compliance

Qualifications:

Bachelors Degree or Masters Degree in Cell/Molecular Biology or a related field with 5 years of relevant experience pharmaceutical industry experience is preferred

Expertise in molecular biology techniques including DNA/RNA extraction and quantification PCR-based assays gel electrophoresis blotting techniques and sequencing analysis

Hands-on experience with mammalian cell culture

Experience with DNA sequence manipulation software and common software packages such as Microsoft Office

Excellent written and interpersonal communication skills with the ability to build strong relationships with peers and cross-functional team members

Strong planning multitasking time management and troubleshooting skills

Collaborative and proactive attitude with strong scientific curiosity work ethic and attention to detail

Authorization to work in the United States is required

Preferred Qualifications:

Experience with expression vector elements construction and molecular cloning

Experience with digital PCR assays such as droplet digital PCR ddPCR

Proven track record in vector biology cell line genetic characterization and/or CHO cell line development
About Actalent
Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 30,000 consultants and more than 4,500 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500.
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At Actalent, diversity and inclusion are a bridge towards the equity and success of our people. DE&I are embedded into our culture through:

• Hiring diverse talent
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The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.

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