Scientist I, Chemical Biology

About InduPro

InduPro is bringing life-changing therapies to patients through novel cell-surface platform technologies. We are defining and manipulating protein interactions beyond natural signaling paradigms. InduPro platforms integrate inherent protein proximity at the cell surface with the ability to manipulate protein pairings via induced protein proximity to create novel signaling pathways and logic gates. Our culture fosters innovation at every level.

The OpportunityThis highly-skilled and innovative thinker will apply chemical biology-based methods that include proximity labeling to profile within biological systems. This role will provide a detailed characterization of the cell surface interactome in the context of tumor and immune cells environments. Using InduPro's novel technologies, we will establish a living database of protein environments across cell types and disease tissues. Experimentation will be in close collaboration with biology, proteomics and protein engineering colleagues as we work to define the cell surface protein interactome for therapeutic discovery and development.

Key Responsibilities

Leverage cutting edge chemical biology techniques to enable proteomics-based workflows for high resolution profiling of protein environments on the cell surface

Design and execute cell surface labeling in mammalian cell culture, primary immune cells and tissues

Apply InduPro platforms for target identification and validation for downstream therapeutic development

Develop sample processing workflows compatible with sensitive proteomic analyses

Prepare protein conjugates for probing cell surface environments

Act as a scientific leader from the bench, driving research, strategies, and ideas to completion

Proactively engage with colleagues from various functions as well as external collaboration teams to integrate proximity labeling technologies for identification and/or validation of proximal protein environments

Contribute to the collective knowledge of multidisciplinary teams through extensive idea exchange and collaboration

Stay current on emerging technologies and provide scientific mentoring and technical training of team members as appropriate

Performs other duties as assigned (required for all roles)

Supervisory Responsibilities

Directs, coordinates, organizes, and prioritizes biological laboratory activities

Physical Work Requirements

Prolonged periods standing, reaching and bending while working in the lab

Requirements

Ph.D. in Biochemistry, Chemical Biology, Immunology, Cell Biology or similar subject areas, with 0-3 years postgraduate experience

Expert-level knowledge and experience in designing and performing chemical biology experiments for mammalian cell and/or tissue systems

Expertise and familiarity with cell culture, immunoprecipitation, standard immunological techniques and immune assays including flow cytometry

A strong record of scientific achievement, including publications in high-impact journals

General knowledge of biology and scientific research methods

Strong critical thinking and evaluative skills

Demonstrated ability to manage research projects

Excellent verbal and written communication skills to collaborate effectively with scientists working in other disciplines

Benefits

At InduPro we believe that being face to face helps enhance collaboration, innovation, productivity, employee well-being, employee engagement, and Company culture. Onsite work is required for this role at our beautiful office location in Cambridge, MA.

Every member of the InduPro team plays a role in shaping our science and our culture in a dynamic startup environment. We offer a competitive total compensation package, including stock options, a comprehensive benefits package, paid time off, relocation assistance, and exciting opportunities for professional development.

Benefits include medical, dental, and vision coverage; company-paid life and disability insurance; supplemental life and disability insurance; voluntary accident, critical illness, and hospital indemnity insurance; a 401(k) plan with employer matching contributions; flexible spending accounts; an employee assistance program; flexible paid time off; 10 paid company holidays; and employee access to voluntary auto, home, legal, and pet insurance.

InduPro, Inc. is an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, age, gender identity, sexual orientation, color, religion, sex, marital status, national origin, protected veteran status, disability, or any other status protected by federal, state, or local law.