Associate Scientific Director, Research- Gamma Delta/Innate Biology and IO Therapies

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Job Description

Are you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine?

At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to realize their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

Here, you will be a vital contributor to our inspiring, bold mission.

OBJECTIVES/PURPOSE

The Cell Engager team of the Oncology DDU is seeking a highly motivated and experienced Associate Scientific Director with demonstrated skills in Gamma Delta Biology and IO therapy. The interested candidate must have deep subject-matter experience developing and advancing Gamma Delta T cell therapies for Oncology, expertise in program/project leadership, target validation, ideation and interrogation of immune cell function and screening of therapeutic candidates. The sucessful candidate will play an integral role in developing Cell Engager and Cell Therapy combination strategies and concepts using blood and skin VD1 cells. As a leader of the CE team, the candidate must demonstrate scientific leadership with deep subject-matter expertise, driving project team progression, and development of technical capabilities including enhancement of innate platform capabilities. Experience in Gamma Delta and/or Innate Biology is strongly preferred. Interested candidates looking to flex their experience in a large pharma with a biotech mindset through internal and external partnerships.

ACCOUNTABILITIES

• This role requires a strong scientific background in the field of immune-oncology (I/O), Gamma Delta Biology or Innate Cell Therapy/engagers in early phase drug discovery as a project team leader (PTL) capable of leading and providing oversight to PTL's or key project team contributors.
• The candidate has a strong Immunology Background and with experience in Gamma Delta biology is strongly preferred
• The candidate enjoys and has experience working collaboratively providing scientific leadership to internal teams and joint research efforts being pursued with our strategic partners in Gamma Delta Biology and Engager platforms
• Lead concepts utilizing VD1 biology for the development of novel CE/CTx combination strategies
• Adapt blood and skin-derived VD1 platform for therapeutic utility in development of cell engager and cell therapy concepts
• Represent project teams and /or CE portfolio to internal leadership and external partners, leads productive discussions on key scientific and strategic issues with internal and external colleagues at all levels and across disciplines.
• Uses enterprise mindset with a broad view across the portfolio that informs resourcing and prioritization of programs under direct remit
• Enables growth of the CE pillar portfolio with new scientific ideas
• Play an active role in the evaluation of potential drug candidates for in-licensing or partnering.
• Serve as a scientific connector who prioritizes rigorous science and development of organizational culture and capabilities
• Contributes to continual deepening of domain expertise through external network
  development; evaluates new opportunities in partnership with business development
• Develops the next-generation of organizational and project leaders, acts as a champion for new opportunities
• Acts as internal key opinion leader for his/her area of technical expertise
• Outstanding expertise and depth of knowledge advancing IO therapeutics from discovery through preclincial proof of concept in support of clinical testing.
• Keeps up with the up-to-date scientific advancement (e.g. competitive landscape, new technology, new research portfolio, and new partnership)
• Scientific leadership role, setting high standards for effectiveness of execution, and rigor of thought
• Has significant managerial responsibility within the CE team
• Independently manages workload and expectations
• Scientifically independent
• Scientific driver for research strategy that impacts group internally and outside area of function
• Initiates and leads external interactions and collaborations
• Frequent contact with internal and external personnel at various management levels
• Celebrates a culture of transparency and accountability with team members at all levels.
• Determines methods on new assignments; makes strategic recommendations on projects

EDUCATION, BEHAVIOURAL COMPETENCIES AND SKILLS:

• PhD degree in a scientific discipline with 7+ years experience, with a minimum of 5 years of drug discovery, including demonstrated leadership of biology and project teams in the biotechnology industry.
• Know-how and experience in VD1 gamma delta and innate biology is strongly preferred
• Knowledge of drug discovery process and pharmacology is essential
• A successful track record of leading preclinical activities to deliver biological assets from lead declaration through to IND / CTA, and ideally beyond into the clinic is preferred .
• Previous experience and success with choosing and managing relations with external contractors, including CROs.
• Excellent team player with a can-do attitude with an ability to thrive in a dynamic "biotech- like" environment and work in cross-functional project teams
• Self-motivated, collaborative with excellent time management and organizational skills with empathetic leadership style.
• Strong leadership and interpersonal skills; the individual should have a track record of developing teams and participating in developing culture and people across an organization.

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

WHAT TAKEDA CAN OFFER YOU:

• 401(k) with company match and Annual Retirement Contribution Plan
• Tuition reimbursement Company match of charitable contributions
• Health & Wellness programs including onsite flu shots and health screenings
• Generous time off for vacation and the option to purchase additional vacation days
• Community Outreach Programs

Base Salary Range: 143,500.00 to 205,000.00 Employees may also be eligible for Short Term and Long-Term Incentive benefits. Employees are eligible to participate in Medical, Dental, Vision, Life Insurance, 401(k), Charitable Contribution Match, Holidays, Personal Days & Vacation, Tuition Reimbursement Program and Paid Volunteer Time Off.

The final salary offered for this position may take into account a number of factors including, but not limited to, location, skills, education, and experience.

Empowering Our People to Shine

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EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

Boston, MA

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time