Research Associate / Senior Research Associate - Biology

Job Title:Research Associate/Senior Research Associate

Location:La Jolla, California

Company Overview

At Avidity Biosciences, we are passionate about the impact of every employee in bringing potentially life-changing therapeutics to patients in need. Avidity is pioneering a new class of oligonucleotide-based therapies called AOCs designed to overcome the current limitations of oligonucleotide therapies to treat a wide range of serious diseases. We utilize our proprietary AOC platform to design, engineer and develop transformative therapeutics that combine the tissue selectivity of monoclonal antibodies (mAbs) and the precision of oligonucleotide-based therapies to access previously undruggable tissue and cell types and more effectively target underlying genetic drivers of diseases. If you are a committed, solution-oriented thinker, come make a difference with us.

Job Summary

We are seeking a highly motivated Research Associate/Senior RA to join our Biology team and contribute to the development of our cardiac therapeutics pipeline. The position requires daily lab work, analyzing data and meeting with key stakeholders to present results, with the goal of contributing high-quality data for pre-clinical drug development. The ideal candidate will be proficient in cellular and molecular biology techniques, precise documentation, demonstrate clear and professional verbal and written communication, and be a strong team player.

Essential Duties and Responsibilities

• Design and perform experiments, analyze data, interpret and report results
• Keep detailed and accurate records in an electronic lab notebook
• Experimental work will comprise: mammalian cell culture (lines and primary cell isolation), transfections, RNA extractions from cells and tissues, gene and protein expression analysis, perform screens and cell based assays in high-throughput format, develop and optimize assays.
• Collaborate and communicate with team members and across departments to deliver corporate goals
• Work with supervisor to prioritize work
• Provide training to new laboratory staff

Qualifications

• A B.S./B.A./M.S. degree in biological sciences with 2-4 years of relevant lab experience, preferably in an industry setting
• Proficient with mammalian cell culture (maintaining cell lines, banking, transfections) under strict aseptic techniques and working in different multi-well formats.
• Experience working with iPSC and cardiomyocytes is a plus.
• Proficient in RNA isolation from cells and tissues, quantitative real-time PCR, ddPCR and Western Blot/Jess.
• Proficient computer and data analysis skills, specifically with Microsoft Office Suite and GraphPad Prism
• Proven ability to conduct self-directed research, and to work effectively in a dynamic environment with a diverse team of co-workers
• Comfortable working on different projects simultaneously

Physical Requirements/Demands

• Repeating motions that may include the fingers, wrists, hands and/or legs
• Remaining in a stationary position, often standing or sitting for prolonged periods
• Adjusting or moving objects up to 50 pounds.
• Operating machinery and laboratory equipment

Environmental Conditions

• Low temperatures

• Noisy environments
• Exposure to general laboratory environment conditions.
• Exposure to general office environment conditions.

Salary Range: $65,000 - $85,000