Associate Scientific Director, Research Next Generation TCE and IO Biology/ Platform Lead

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Job Description

Are you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine?

At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to realize their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

Here, you will be a vital contributor to our inspiring, bold mission

OBJECTIVES/PURPOSE

The Cell Engager team of the Oncology DDU is seeking a highly motivated and experienced Assocciate Scientific Director with demonstrated skills in IO and Cell Engager therapies. The interested candidate must have deep subject-matter experience developing and advancing Immunobiologics for Oncology, expertise in program/project leadership, target validation, ideation and interrogation of immune cell functon and screening of therapeutic candidates. As a leader of the CE team, the candidate must demonstrate scientific leadership with deep subject-matter expertise, driving project team progression and development of technical capabilities. As a key member of the team, the candidate will be responsible for assessing therapeutic concepts and strategy, various immune engager molecules and advancing novel research molecues towards development candidates and IND. Experience in Bispecifics and Multispecifics spanning Innate and Adaptive mechanisms is strongly prefererd. Interested candidates looking to flex their experience in a large pharma with a biotech mindset through internal and external partnerships.

ACCOUNTABILITIES

This role requires a strong scientific background in the field of immune-oncology (I/O) and in early phase drug discovery as a project team leader (PTL) capable of leading and providing oversight to PTL's or key project team contributors in a direct and matrixed structure.
The candidate must have strong backgournd in cancer biology and therpies, with experience in IO biology is strongly preferred
The candidate enjoys and has experience working collaboratively providing scientific leadership to internal teams and joint research efforts being pursued with our strategic partners for TCE, Myeloid and other Innate Engager paltforms
Represent project teams and /or CE portfolio to internal leadership and external partners, leads productive discussions on key scientific and strategic issues with internal and external colleagues at all levels and across disciplines.
Scientific driver for research strategy that includes ideation and lead design strategy and implementation of new immune engager concepts (may not be limited to T cells alone) with an initial focus on COBRA iterations as a T cell engager to impact pipeline
Oversees various aspects of COBRA iterations: assay design, optimization, validation and implementation as it relates to T cell activation, co-stimulation and related cancer cell targeting and cytotoxicity
Uses enterprise mindset with a broad view across the portfolio that informs resourcing and prioritization of programs under direct remit
Enables growth of the CE pillar portfolio with new scientific ideas
Serve as a scientific connector who prioritizes rigorous science and development of organizational culture and capabilities
Contributes to continual deepening of domain expertise through external network
development; evaluates new opportunities in partnership with business development
Develops the next-generation of organizational and project leaders, acts as a champion for new opportunities
Acts as internal key opinion leader for his/her area of technical expertise
Outstanding expertise and depth of knowledge advancing IO therapeutics from discovery through preclincial proof of concept in support of clinical testing.
Keeps up with the up-to-date scientific advancement (e.g. competitive landscape, new technology, new research portfolio, and new partnership)
Scientific leadership role, setting high standards for effectiveness of execution, and rigor of thought
Has significant managerial responsibility within the CE team
Independently manages workload and expectations
Scientifically independent
Scientific driver for research strategy that impacts group internally and outside area of function
Initiates and leads external interactions and collaborations
Frequent contact with internal and external personnel at various management levels
Celebrates a culture of transparency and accountability with team members at all levels.
Determines methods on new assignments; makes strategic recommendations on projects

EDUCATION, BEHAVIOURAL COMPETENCIES AND SKILLS:

PhD degree in a scientific discipline with 7+ years experience, with a minimum of 5 years of drug discovery, including demonstrated leadership of biology and project teams in the biotechnology industry.
Knowledge of drug discovery process and pharmacology is essential
A track record of driving projects to IND is essential and/or strongly preferred.
Previous experience and success with choosing and managing relations with external contractors, including CROs.
Excellent team player with a can-do attitude with an ability to thrive in a dynamic "biotech- like" environment and work in cross-functional project teams
Self-motivated, collaborative with excellent time management and organizational skills with empathetic leadership style.
Strong leadership and interpersonal skills; the individual should have a track record of developing teams and participating in developing culture and people across an organisation

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

WHAT TAKEDA CAN OFFER YOU:

401(k) with company match and Annual Retirement Contribution Plan
Tuition reimbursement Company match of charitable contributions
Health & Wellness programs including onsite flu shots and health screenings
Generous time off for vacation and the option to purchase additional vacation days
Community Outreach Programs

Base Salary Range: 143,500.00 to 205,000.00. Employees may also be eligible for Short Term and Long-Term Incentive benefits. Employees are eligible to participate in Medical, Dental, Vision, Life Insurance, 401(k), Charitable Contribution Match, Holidays, Personal Days & Vacation, Tuition Reimbursement Program and Paid Volunteer Time Off.

The final salary offered for this position may take into account a number of factors including, but not limited to, location, skills, education, and experience.

Empowering Our People to Shine

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EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

Boston, MAWorker Type

EmployeeWorker Sub-Type

RegularTime Type

Full time