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Post Doc Scientist (Cryo-EM), Structural Biology & Chemistry

Foster City, California, US
Closing date
May 27, 2023

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Academic / Research
Conservation science
Salary Type
Employment Type
Full time
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Job Description

The Structural Biology Group at Gilead Sciences is seeking a highly motivated cryo-EM postdoc to join our program at the Foster City campus. The Structural Biology Group is well equipped with an advanced X-ray crystallography laboratory and is building a state-of-the-art cryo-EM facility with a Glacios and a Krios G4 microscopes. The group provides critical structural information to elucidate the mechanism of action and to facilitate lead molecule optimization, and supports diverse drug discovery projects spanning virology, inflammation, and oncology.

This postdoc position will be utilizing protein biochemistry, biophysics, and cryo-EM techniques to elucidate the molecular mechanism of important drug targets including both small molecule and biologics programs. As part of the training, the candidate will also contribute to the new cryo-EM methods development and implementation.

The successful candidate is expected to have a solid training in single particle cryo-EM and strong scientific experience as evidenced by first-author publications in top-tier scientific journals.


Construct design, protein expression and purification for structural studies.

Cryo-EM sample preparation & optimization, data collection and structure determination of target complexes.

Basic Qualifications:

Candidates must have Ph.D in structural biology, biochemistry, or a related field.

Preferred Qualifications:

Experience in laboratory techniques supporting structural biology and recombinant protein purification, membrane protein experience is highly desired.

Strong communication and interpersonal skills, and the ability to work flexibly in a dynamic and collaborative environment.

Demonstrated a strong track record of independent critical thinking and scientific achievement in research, exemplified by publications in highly regarded journals, conference presentations or generation of intellectual property.

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Please log onto your Internal Career Site to apply for this job.

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