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Principal Scientist, Early Biology

Cambridge, Massachusetts, US
Closing date
May 28, 2023

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Principal Scientist, Early Biology at Relay Therapeutics

We are seeking an innovative and motivated cell/molecular biologist to join our growing Early Biologyteam.The successful candidate willlead activities toidentifyand evaluate target dependency hypotheses,help identify preclinicalmodelsrepresentative of target patient populations, andvalidate small molecule leads.We are looking for youtohelp shape our growing portfolio andprovide intellectual and strategic leadership as weselect and execute on our next wave(s) of targets that will benefit patients.Youwillwork collaboratively within an energetic, matrixed research organization,helping guideteams and communicate the importance of our work to a broad audience.

Your Role:
  • Serveas the Biology lead on teams passionate about developing small molecule modulators of clinically validated targets
  • HelpIdentify the best targets to expand our portfolio and designbiology experiments to assess targetdependencyand function
  • Develop and validate cell-based models,evaluate candidate small molecules,and supportourdrug discoveryefforts
  • Direct and indirect leadership of individualsand managing external CROsto drive our projects

Your Background:
  • Youhaveearned your Ph.D. and have post-doctoral training in genetics/cell/molecularbiology or related field
  • You have proventrackrecord of excellence as evidenced by high impact, peer reviewed publications
  • You have at least 8+ years of experience in biotech/pharma
  • You have experience with cell line profiling, pathway signaling, understanding of genomic drivers, assay development, and compound profiling
  • You can thrive in a dynamic environment, are detail oriented, and are a problem-solver; a strong work ethic and high-level motivation are required
  • You are a great communicator, able to share the impact of efforts and motivate others do great science
  • You are eager to deepen your (and our) understanding of targets and the small molecule drug discovery process

About Relay Therapeutics

Relay Therapeutics is a clinical-stage precision medicines company transforming the drug discovery process with the goal of bringing life-changing therapies to patients. Built on unparalleled insights into protein motion and how this dynamic behavior relates to protein function, we aim to effectively drug protein targets that have previously been intractable, with an initial focus on enhancing small molecule therapeutic discovery in targeted oncology. Our Dynamo platform integrates an array of leading-edge experimental and computational approaches to provide a differentiated understanding of protein structure and motion to drug these targets. We have built a world-class team of leading experts from each of these disciplines, and they are driven by a deep collaboration at every step of our drug discovery process.

Our team is equal partsfearlessandrelentless, with a shared passion for working collaboratively in intellectually stimulating environments. If you're excited by the challenge of putting protein motion at the heart of drug discovery and passionate about making a difference in the lives of patients, join us!

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