Senior Associate Scientist - Molecular Biology

Job Summary

At Sanofi we are committed in our quest to be a world-class biologics research organization and are steadfast in our goal to bring next generation, transformative therapies to patients. Our global Large Molecule Research (LMR) platform consists of five sites, and approximately 550 personnel focused on antibodies, NANOBODY® molecules and synthorins™ as therapeutic modalities. Our platform enables and partners closely with other research platforms and Sanofi's therapeutic areas (Immunology & Inflammation, Immuno-Oncology, Rare & Neurologic Diseases) in the discovery and ultimate delivery of new candidate molecules.

We are seeking a talented and highly motivated scientist to join our dynamic team in the Molecular, Expression and Screening Technologies (MEST) Group within Sanofi's North America R&D LMR organization. The MEST group uses cutting-edge automated systems for molecular biology, protein production and screening. The automated platforms within the group allow for the standardization of highly complex protein engineering workflows thus enabling the rapid discovery of next generation multi-specific protein therapeutics. The individual in this position will be responsible for the operation and maintenance of our automated molecular biology platform. The large numbers of recombinant plasmids generated on the automated molecular biology platform will be used for expressing proteins/antibodies (including multi-specific protein therapeutics) on the established automated protein expression and purification (PEPP) system. This person must have strong molecular biology and automation skills, the ability to work in a fast-paced environment while maintaining a high level of attention to detail, and the ability to organize and present data. The person in this role must have the ability to work in a collaborative team environment and to communicate effectively both within the immediate group and across groups.

Knowledge and Skills

Required

• Strong molecular biology skills including Gateway, InFusion and Gibson Assembly cloning technologies, knowledge in plasmid construct design (including antibodies), agarose gel electrophoresis, DNA purification, DNA sequencing and sequence analysis
  
• Extensive experience with molecular biology software such as Sequencher, SnapGene or Geneious
  
• Experience with automation and high throughput instrumentation including liquid handlers (example: Tecan/Hamilton).
  
• Ability to work with LIMS (Laboratory Information Management System) and biological registration systems (example: GeneData Biologics)
  
• Ability to transform and analyze large datasets through a variety of methods (example: Spotfire)
  
• Must be proficient with Microsoft Excel and other Microsoft Office applications
  
• Detail-oriented, strong skills in organization, time management, and teamwork are essential
  
• Excellent interpersonal, communication and presentation skills
  

Preferred

• Experience with developing new methods for automation equipment, particularly liquid handlers
  

Experience Required

• BS or MS in biology or related field and 4-6 years of experience in a research laboratory or a biopharma/biotech company.
  

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.