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Research Fellow - Kozin Neurobiology and Traumatic Brain Injury Research (Full-time)

Employer
Mass. Eye and Ear
Location
Boston, Massachusetts, US
Salary
Competitive
Closing date
Dec 5, 2022

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Sector
Academic / Research
Field
Conservation science
Discipline
Genetics, Biology
Salary Type
Salary
Employment Type
Fellowship, Full time
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Job DescriptionThe Kozin laboratory in partnership with the Polley laboratory at Massachusetts Eye and Ear is looking to hire a research technologist for neurobiology research in mice. The candidate would lead new investigations into the brain's endogenous pathways and mechanisms for sensory plasticity. The research technologist would be an intergral member of a small team working on new approaches to leverage the brain's endogenous neuromodulatory systems as a new approach to sensory rehabilitation. The research technologist would perform pioneering research using a wide-range of modern in vivo neuroscience techniques such as 2-photon calcium and biosensor imaging, multi-channel neurophysiology, fiber-based imaging, optogenetics, operant behavior and quantitative videography assisted by machine learning. The research technologist will maintain critical laboratory equipment and train new laboratory members on their proper use. The research technologist will be responsible for data analysis, some figure preparation, and will be a co-author on resultant publications. Their work could lead to new treatment avenues for "sensory overload", a debilitating condition commonly found in traumatic brain injury, post-traumatic stress disorder, sensorineural hearing loss, and normal aging. This is a longer staff position supported by a stable source of funding intended for someone looking to make a career in neuroscience laboratory research. It is not intentended as an interim research assistant position.

ESSENTIAL FUNCTIONS:
  • Records and graphically displays pertinent information obtained from research activities, through preparation of charts, illustrations, slides, statistical summary graphs, and narrative reports. Provides information that will typically be used as a basis for further investigation and/or for inclusion and co-authorship on resultant publication(s).
  • Carries out cutting-edge laboratory experiments including small animal survival surgeries, in vivo imaging, in vivo neurophysiology, animal behavior, and advanced data analysis.
  • Trains new graduate students, postdoctoral fellows and research assistants on the safe and effective use of advanced neuroscience lab equipment such as multi-photon imaging systems and opto/electrophysiology systems.
  • Calibrates laboratory equipment and coordinates equipment servicing or replacement.


Qualifications
Requires a Ph.D in their field of specialty. 1 to 5 years experience preferred. Preference will be given to candidates with a strong track record studying brain physiology and behavior with as many of the following techniques as possible: 2-photon imaging, electrophysiology, fiber imaging, optogenetics, operant behavior and quantitative videography assisted by machine learning. Strong candidates will have some experience writing custom scripts for data analysis in Matlab, Python, or a related programming environment.

WORKING CONDITIONS:

Spends time between the wet laboratory, the animal housing facility, and an office adjacent to the laboratory, equipped with a personal computer for data entry and analysis.

PHYSICAL REQUIREMENTS:

Able to work with animals (rodents), lifting animal cages onto a cart, performing routine animal injections, assisting in animal surgery. Manipulates fine surgical instruments, perform routine animal injections, and perform animal survival surgery. Load cages onto a cart and transport them between the animal facility and the laboratory.

EEO Statement
Massachusetts Eye and Ear is proud to be an equal-opportunity employer and is committed to providing a workplace free from harassment or discrimination. All employment decisions are made without regard to race, color, age, gender, gender identification, sexual orientation, religion, marital status, sex, pregnancy or conditions related to pregnancy, national origin/ancestry, citizenship, disability, military status, genetic information, or any other basis prohibited by law. These protections extend to all management practices and decisions, including recruitment and hiring practices, appraisal systems, promotions, training, and career development programs Partner's Healthcare is acting as an Employment Agency in relation to this vacancy.
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