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Senior Research Associate, Cell Biology - 2346

Employer
Editas Medicine
Location
Cambridge, Massachusetts, US
Salary
Competitive
Closing date
Dec 6, 2022

View more

Sector
Academic / Research
Field
Conservation science
Discipline
Biology
Salary Type
Salary
Employment Type
Full time
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Job Description
What if you could repair broken genes? That is the question we ask ourselves at Editas Medicine. We're focused on translating the power and potential of the CRISPR/Cas9 and CRISPR/Cpf1 (also known as Cas12a) genome editing systems into a robust pipeline of medicines for people living with serious diseases around the world. Our goal is to discover, develop, manufacture, and commercialize transformative, durable, precision genomic medicines for many diseases. We're looking for talented, dedicated, passionate people to join our team and help us pioneer this field and do big, bold things that have never been achieved before. Are you full of hope, possibilities, and a belief that, working together, we can truly revolutionize the development of medicines to help patients around the world? If the answer is yes, then Editas Medicine is the place for you.

Editas Medicine is seeking a highly motivated in vitro cell biologist at the level of Senior Research Associate to join our Gene Editing Target Research group. In this role, you will support on-going efforts to develop gene editing therapies for exploratory new targets in various tissues and organs. You will contribute to the development of cell-based assays to evaluate the extent and effects of gene editing. An ideal candidate should have a background in primary cell culture (e.g., primary hepatocytes, ocular cells, or stem cells), microscopy, and molecular biology, as well as a track record of creative thinking and a strong interest in genome editing. The successful candidate will be part of a dynamic, multidisciplinary discovery team dedicated to the development of gene editing-based therapies for major disease indications.

Key Responsibilities:
  • Develop and optimize primary cell-based assays
  • Formulate lipid nanoparticles for cell transfections
  • Plan, perform, and analyze DNA/RNA extraction, qPCR, and ddPCR experiments
  • Develop and optimize protein quantification assays such as Western blot and ELISA
  • Perform flow cytometry and microscopy, including high content imaging and analysis
  • Analyze and present data within the organization
  • Share responsibility in maintaining lab equipment and reagent inventory
  • Maintain an electronic lab notebook and contribute supporting documentation

Requirements

Minimum Requirements:
  • BS and 2+ years or MS and 1+ years in cell biology or related field with laboratory experience in the biotechnology or pharmaceutical industry
  • Experience with mammalian cell culture, including primary cells (especially primary hepatocytes
  • Molecular biology experience (ddPCR, qPCR)
  • Results-driven with excellent attention to details and ability to independently execute protocols
  • Excellent written and oral communication skills
  • Ability to work in a team-oriented, multidisciplinary environment

Preferred Qualifications:
  • Experience with formulating and working with lipid nanoparticles
  • Experience troubleshooting assays, including conducting scientific literature searches and reviews
  • Immunoassay experience (immunofluorescence, Jess automated Western Blot and ELISA)
  • Flow cytometry and microscopy experience
  • Experience with automation

Benefits

Benefits Summary:

Editas provides a comprehensive array of benefits to all employees, including a Blue Cross Blue Shield PPO Medical Plan, a company-funded Health Savings Account, Dental and Vision Insurance, Life and Disability Insurance, Dependent Care Account, Tuition Reimbursement, 401(k) plan with company match, Employee Stock Purchase Plan, Employee Assistance Plan, Wellness Programs, and a flexible Paid Time Off policy.
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