Oncology Discovery Biology Co-op - Spring 2023

At Bristol Myers Squibb, we are inspired by a single vision - transforming patients' lives through science. In oncology, hematology, immunology and cardiovascular disease - and one of the most diverse and promising pipelines in the industry - each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

The Mechanisms of Cancer Resistance Thematic Research Center at BMS is one of the fundamental research and early development engines delivering oncology therapeutics to patients. The scientists at this state-of-the-art research and development site in Cambridge focus on novel tumor intrinsic targets and pathways for tumors that are refractory to current Immuno-Oncology and Oncology therapies. We are a fully integrated drug discovery through translational and early clinical development organization which exploits state-of-the-art in vitro, in vivo and ex-vivo models of cancer biology to identify and validate targets. We are optimally positioned to complement the world-class translational expertise, biology and leading academic research centers in the area.

Join us and make a difference.

Position Summary

This entry-level laboratory-based position requires a highly collaborative, motivated, passionate, and creative individual that possesses the ability to work across a highly matrixed environment to advance preclinical programs from target validation through IND enabling activities. The ideal candidate will have experience in laboratory-based biology research. This position will offer the candidate the opportunity to develop antibody-based therapeutics delivering novel payload classes while developing strong collaborations with colleagues from our supportive line functions (including medicinal chemistry, screening, in vivo pharmacology and translational research). In addition to working on scientific projects, the candidate will have ample opportunities to participate in discovery working groups and project teams and to gain a better understanding of the drug discovery process.

Key Responsibilities

• Maintain cancer cell cultures and genetically engineer cell lines
• Establish 3D spheroid models for ex-vivo evaluation of ADC tumor penetration and bystander kill
• Develop ex-vivo tumor:immune co-culture systems for assessing ADC effector function and synergies with immune checkpoint inhibitors
• Analyze, graph and present data at small group meetings and broader BMS forums

Qualifications & Experience

• Active pursuit of a BS/MS in biology, biochemistry, biotechnology or biomedical engineering.
• Laboratory experience with hands-on research experience in cancer biology, cell signaling or molecular biology.
• Experience with in vitro cell culture, cell line engineering is preferred.
• Experience with flow cytometry and imaging platforms preferred.
• Motivated to develop independence in experimental design, execution, data analysis and troubleshooting is required.
• Proficiency in utilizing software such as Graph Pad, Microsoft office etc. for data analysis, figure generation and data presentation.
• Attention to detail with excellent organizational and record keeping skills is a must.
• Excellent interpersonal skills with the ability to interact effectively with BMS employees is required.
• This position is located in Cambridge, MA.

Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture.

To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.

Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application or if you are applying to a role based in the U.S. or Puerto Rico and you believe that you are unable to receive a COVID-19 vaccine due to a medical condition or sincerely held religious belief, during or any part of the recruitment process, please direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

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