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Scientist / Sr. Scientist - Molecular Biology

Employer
Serotiny
Location
South San Francisco, California, US
Salary
Competitive
Closing date
Nov 28, 2022

View more

Sector
Consultancy/Private Sector
Field
Conservation science
Discipline
Biology
Salary Type
Salary
Employment Type
Full time
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Scientist / Sr. Scientist - Molecular Biology
Serotiny invents multi-domain proteins for gene and cell therapies including genome editors, and chimeric antigen receptors. These novel synthetic proteins are central to cutting edge therapeutics, providing enhanced safety and efficacy through advanced control methods and engineered functionalities. We strategically couple synthetic biology with data science and machine learning to generate large-scale protein libraries for high-throughput screening and analysis.
As a Scientist joining Serotiny you'll work at the intersection between protein engineering, preclinical development, and high-throughput screening to build out and deploy Serotiny's novel methods to characterize and develop cutting edge therapeutics. You'll work hand-in-hand with groups across disciplines to ensure that no candidate goes un-interrogated.

Role

* Lead from the bench in the design, manufacture and functional screening of novel CAR constructs discovered using Serotiny's high-throughput platform
* Independently execute and troubleshoot molecular biology projects to support the laboratory team
* Introduce techniques and protocols to enable library assembly and implement quality control metrics
* Work closely with team members to understand details of ongoing gene editing and cell engineering projects
* Maintain excellent electronic lab notebook records of protocols and experimental details
* Collaborate with software engineers to develop the design and analysis methodologies and pipeline
* Participate in team meetings and provide regular oral and written communication on all projects and milestones to relevant project team

Qualifications

* Degree in molecular biology, cell biology, biotechnology or related area
* Scientist: BSc. with >6 years of experience, or MSc. with >4 years of experience, or Ph.D.
* Sr. Scientist: BSc. with >10 years of experience, or MSc. with >7 years of experience, or PhD. with >2 years of industry or other relevant experience
* Hands-on experience with next gen sequencing library preparation and execution
* Extensive experience with molecular cloning techniques, plasmid DNA preparation, mammalian cell culture, cell transfection, viral production and QC
* Hands-on experience with next gen sequencing library preparation and execution
* Extensive experience with molecular cloning techniques, plasmid DNA preparation, mammalian cell culture, cell transfection, viral production and QC
* In-depth knowledge and experience with immunostaining methods, flow cytometry, and FACS
* Experience in high-throughput protein engineering approaches is a plus
* Strong communication skills with proven experience in collaborating across disciplines
* Excellent organizational skills, detail oriented and an ability to prioritize effectively to deliver results within reasonably established timelines
* Comfortable to work in a fast-paced startup environment with minimal direction and able to adjust workload based upon changing priorities
* Candidates must be authorized to work in the US

Perks

* Full health benefits
* 401(k) with employer match
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