Job DescriptionSalary: The Company
Vaccitech plc is a fast-growing biotech company. At only six years old we already have a development portfolio of nine programmes, including a partnered product that is in commercial production and that has seen more than 3 billion doses administered worldwide and an IPO behind us. We are a publicly-listed clinical stage biopharmaceutical company that spun out of the University of Oxford's Jenner Institute, one of the most prestigious vaccine research centres in the world. We discover and develop immunotherapeutic products and vaccines for the treatment and prevention of infectious diseases, cancer, and autoimmunity. Our achievements include co-inventing and jointly developing our COVID-19 vaccine candidate VTP-900, now Vaxzevria, which we assigned to Oxford University Innovation to facilitate the licensing of those rights to AstraZeneca. We run clinical studies to explore treatments for patients with HBV and HPV infections and are developing rapid and scalable manufacturing processes for our platforms.
In December 2021, Vaccitech acquired Avidea Technologies Inc. with exciting product candidates for oncology and autoimmunity based on the innovative SNAPvax platform, which has demonstrated unprecedented control over T cell induction. This enhances our U.S operational presence in Maryland, complements Vaccitech's established capabilities and reinforces our position as a fast-growing global leader in immunotherapies and vaccines. Vaccitech's UK headquarters has recently moved to a state-of-the-art facility in the UK's leading science and innovation campus at Harwell. We conduct research globally and have ambitious plans in the UK and US, where we will continue to grow our teams over the coming months and years.The role
Vaccitech are actively seeking an expert in flow cytometry
to join them as a Senior Biologist on a full time permanent basis. Reporting to the Head of Antibody Vaccine R&D, the Senior Biologist will be responsible for conducting immunological assays to support the preclinical development of immunotherapies as part of a multi-disciplinary team of chemists, immunologists, and engineers. The position will also require adequate experience with immunoassays to train junior staff. The primary focus will be on flow cytometry-based assessment of primary immune tissues
to help guide the development of vaccines for the treatment of cancer and autoimmune diseases. The role will be primarily laboratory-based, but there will be opportunities for planning, presentation, and strategy with acquired experience.Key responsibilities include
Qualifications and experience required
- Perform preclinical studies to include coordinating work at CROs, processing of tissue, flow cytometry staining, ELISAs, data acquisition
- Analyze acquired data, synthesize findings, and recommend next steps in regular written and oral presentations
- Provide training to junior staff relating to immunoassays, data generation and reporting results
- Manage and organize immunology/biology lab inventories, instrumentation, and spaces
- Work with the immunology team to help design research studies in animal models to identify lead products for advancement to clinical trials
- Interface with the chemistry team to set priorities for synthesis and testing of candidate immunotherapies
The successful candidate will be degree educated in immunology, biology, or related discipline. Flow cytometry experience is critical to this hire so only candidates with an extensive flow cytometry background need apply.
You must have at least 5 years' lab experience in the conduct of immunological assays, preferably including:
What we can offer
- Preparation of immune cells from animal or human tissues and cell culture
- Flow cytometry (staining, collection, and analysis) (required)
- Cell culture
- ELISAs (preferred)
- Fluorescence microscopy
Vaccitech is a great place to work. We encourage an entirely flat structure with an open door policy to the senior leadership team. Our employees agree the culture and working environment is one of the best things about our business. As part of a small high growth business you will get the opportunity to be involved in many different areas and our rapid growth trajectory means you will have the opportunity to grow with us. We offer employer funded health, dental and vision insurance; a 401k retirement plan; career development opportunities and paid time off (PTO). Salary will be commensurate with experience.Application procedure and timeline:
Notice to Recruiters
- Please use your cover letter to highlight prior immunology lab experience.
- Interviews will occur on a rolling basis and employment can begin as soon as possible.
Vaccitech's internal Talent Acquisition leads recruitment and employment for Vaccitech. Unsolicited resumes sent to Vaccitech from recruiters do not constitute any type of relationship between the recruiter and Vaccitech and do not obligate Vaccitech to pay fees should we hire from those resumes. Vaccitech operate a preferred list of recruitment suppliers, any and all equiries about joining us as a supplier should be directed to Vaccitech's TA Team. We ask that external recruiters and/ or agencies not contact or present candidates directly to our hiring manager or employees.