Senior Associate Scientist / Scientist, Process Biology

Job DescriptionSalary: $100,000 - $150,000

Senior Associate Scientist/Scientist, Process Biology

About Sonoma Biotherapeutics:

Sonoma Biotherapeutics is a South San Francisco and Seattle-based company leading the development of adoptive Treg therapies cell for autoimmune and degenerative diseases. Using next-generation genome editing and target-specific cell therapy, Sonoma is focused on developing its best-in-class platform across the entire spectrum of Treg cell therapeutic capabilities. Founded by pioneers in Treg biology and cell therapy, the company brings together leading expertise and proprietary methodologies for the discovery and development of disease modifying and curative therapies. More information at www.sonomabio.com.

Job Purpose/Summary:

Sonoma Biotherapeutics is seeking a motivated Senior Associate Scientist / Scientist to join our fast-growing and well-organized team to build the best-in-class regulatory T cell therapies for autoimmune diseases. This individual will join the Process Biology team and will assist in establishing the capabilities to characterize cell products via genetic or molecular methods for understanding the biology behind Sonoma procedures and products. In addition, consistent coordination across Sonoma from early research to manufacturing in developing Sonoma processes and help with daily laboratory routines. In this position, the candidate will have the opportunity to utilize cutting-edge Treg science and cellular techniques to develop the next generation of cell therapies for autoimmune diseases and participate the communication of interdisciplinary teams.

Roles and responsibilities:

• Execute the processes of Sonoma pipelines via company standard procedures/developing protocols.
• Perform developed QC assays such as cellular phenotyping, cell expansion, and ELISA.
• Facilitate and develop procedures/protocols to expand the capabilities of product characterization via FACS, qPCR and/or high-throughput screening (RNA-seq and ATAC-seq etc.).
• Coordinate with colleagues to organize workflow and SOP documentation.
• Maintain and document daily activities.

Qualifications and Education Requirements:

• Sr Associate Scientist - BS/MS degree or higher with hands-on bench experience in Biological Sciences such as aging biology, immunology, biotechnology or a related discipline.
• Scientist - BS/MS/PhD degree with hands-on bench experience.
• >3 years of multi-color flow cytometry experience is required.
• 1-3 years of molecular biology experience (DNA methylation, PCR and qPCR etc.) is required.
• Experience with processing human blood and primary T cell isolation/culture is required.
• Strong scientific understanding and logical thinking are required.
• Excellent verbal and written communication skills with the ability to analyze/present data and write reports efficiently.
• Agile mindset and comfortable in a rapid-moving team and a highly productive environment.

Preferred Skills:

• >3 years industrial laboratory experience is preferred.
• Experience with characterizing cellular senescence via genetic/molecular assays is a plus.
• Experience with library prep of high-throughput analysis like RNA-seq or ATAC-seq is preferred.
• Experience with data analysis software such as Prism or JMP is a plus.
• Familiarity with ELN system is a plus.

A day in the life:

The day-to-day life of a team member of Process Biology is operating the processes of Sonoma Treg products with our established SOPs, and develop genetic/molecular methods for product characterization. As the member of Process Biology, you will have hand-on experiences of industrial procedure/documentation of Treg production and development of feasible methods to dissect Sonoma products via Sonoma procedures, and coordinate with product team to improve procedures of pipeline at Sonoma Biotherapeutics.

Sonoma Biotherapeutics is an Equal Opportunity Employer

At Sonoma Biotherapeutics, we believe that the highest performing teams include people from a wide variety of backgrounds and experiences who respectfully challenge each other. We are committed to building an open, diverse, and inclusive culture for all employees.

Sonoma Biotherapeutics is proud to be an equal opportunity employer and does not discriminate on the basis of race, color, citizenship status, national origin, ancestry, sex, sexual orientation, age, religion, creed, physical or mental disability, medical condition, marital status, veteran status or any other characteristics protected under applicable federal, state and local laws.

We've learned from experience that some of the best people don't always match our requirements perfectly - if you're interested and think you could fit, please don't hesitate to apply. Please submit your resume along with a cover letter to careers@sonomabio.com - resumes may also be submitted without applying for a specific job.

If you are an individual with a disability and require a reasonable accommodation to complete any part of the application process or are limited or unable to access or use this online application process and need an alternative method for applying, please contact us at careers@sonomabio.com.