Scientist, Discovery Biology Immunology

Job Description
We are seeking a biologist with a background in inflammation/immunology or immune-oncology to join our culture of transparency, intensity, scientific rigor, and fun! The successful candidate will serve as an integral member of a multidisciplinary pre-clinical team that is developing novel small molecule inhibitors for monoARTs. The position is an opportunity to perform in a high visibility role with the possibility to have a major impact in the pre-clinical stages of drug development. Candidates with a track record in early-stage drug discovery research in either a pharma setting or in academia will be considered.

Responsibilities

• As a lab-based scientist, the candidate will work as part of a pre-clinical team to support ongoing drug discovery, pre-clinical, and clinical programs.
• The candidate will independently evaluate the literature and design/execute/interpret cell-based assays, using mouse and human primary cells and cell lines, to drive mechanism of action studies.
• The candidate will be provided opportunities to manage outsourced FTEs and projects at appropriate CROs.
• The candidate will communicate scientific results among the scientific teams.

Requirements

• MS/Ph.D. in immunology, inflammation, cancer biology, cell biology, biochemistry, or a related field.
• A minimum of 5 years of relevant laboratory experience.
• 0-3 years of drug discovery experience in biotechnology or pharmaceutical industry.
• Extensive mammalian tissue culture experience is required. Experience isolating and culturing primary human and mouse immune cells is a plus.
• Experience with flow cytometry, transcriptional analysis (qPCR), protein and cytokine measurements (ELISA/Luminex/MSD) are required.
• Hands-on experience in immunology/inflammation is an advantage.
• Expertise in cell biology, biochemistry, molecular biology, and genome editing are desired.
• Proven experience in the critical and independent evaluation of the scientific literature is a must.
• Proficient in experimental design, assay development, execution of experiments, data analysis, interpretation, and presentation.
• Excellent problem-solving skills and an ability to take on new challenges.
• The successful candidate is able to work independently yet thrives in a team environment.
• Ability to work well under pressure and drive projects that affect critical timelines.
• Excellent organizational skills and attention to detail.

About Ribon Therapeutics

Ribon Therapeutics is a biotechnology company pioneering the discovery of new cancer medicines that target monoPARP proteins, critical regulators of cancer survival mechanisms. Ribon offers a fast-paced, team-oriented work environment and a comprehensive benefits package, including health, dental, 401(k), paid vacation, and much more. Ribon is located in Cambridge, Massachusetts.

Ribon Therapeutics is an equal opportunity employer.

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