Pioneering technologies to treat or prevent cancer and infectious diseases, we are seeking an experienced research associate to work on our science team. A background in molecular biology is required. The candidate's know-how and critical thinking will help foster a culture of collaboration, innovation, and scientific excellence in our team. This individual will make an immediate impact by contributing to ongoing efforts in developing COVID-19, influenza, and other infectious disease vaccines and therapeutics.Principal Responsibilities:
- RNA preparation, including DNA cloning, DNA linearization, RNA transcription, RNA capping, and RNA purification.
- Characterize protein expression in vitro by cell culture transfection, and SDS-PAGE/western blot, IFA etc analyses.
- Prepare and characterize recombinant virus in vitro.
- Characterize virus isolates as well as recombinant viruses by traditional virological methods. including plaque assay, growth curve analysis, cell impedance-based pathology quantification.
- Design reporter viruses and associated assays for measurement of reporter protein expression.
- Design novel virus phenotyping assays.
- Collaborate with team members to study the impact of the innate immune system on virus replication and heterologous protein expression.
- Work collaboratively with scientists in the team, performing tasks with minimal supervision.
- Monitor and purchase supplies needed to perform daily tasks by cooperating with other co-workers.
- Communicate regularly with management and supervisors.
- Maintain the highest standards of laboratory practice in line with policy, including the maintenance of a laboratory notebook.
- Contribute freely to the team research environment in a manner conducive to the success of the research project as a whole.
- 1-3 years full-time laboratory experience with molecular biology technical experience.
- Proficiency in PCR, cloning, aseptic cell culture, and protein characterization such as SDS-PAGE/ western blot required.
- Experience in immunology, virology, vaccinology or related research field would be preferred but not necessary.
- Excellent oral and written communication skills.
- Computer literacy and proficiency in MS Office programs.