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Bioinformatician / Computational Biologist / - Blood Biopsy Group

Employer
The Translational Genomics Research Institute
Location
Phoenix, Arizona, US
Salary
Competitive
Closing date
Oct 4, 2022

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Sector
Academic / Research
Field
Informatics / GIS
Discipline
Other
Salary Type
Salary
Employment Type
Full time
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DescriptionThe Blood Biopsy Group within TGen's Center for Noninvasive Diagnostics invites
applications for a Bioinformatic and/or Computational Scientist. The goal of this position
is to lead implementation of DNA sequencing data analysis is support of academic
research projects focused on implementing cutting edge technologies such as TARDIS
for analysis of circulating tumor DNA in patients with cancer. The successful candidate
will deploy existing pipelines and develop improvements of analysis of whole genome,
whole exome and targeted sequencing data from tumor, germline and plasma DNA
samples. They will coordinate with the laboratory team to ensure successful design of
personalized assays, implementation of the project and analysis workflow, and
organization and delivery of results. The will contribute to interpretation of findings and
development of publications describing advances in genomics-enabled diagnostics.

You can learn more about TARDIS, a personalized technology for liquid biopsies,
through the manuscript and the following press releases:
https://stm.sciencemag.org/content/11/504/eaax7392
https://www.tgen.org/news/2019/august/07/new-ctdna-blood-test-for-cancer/
https://www.tgen.org/news/2021/january/13/exact-sciences-licenses-tardis/

Duties and Responsibilities:

Experiment design, execution and data analysis.
Development, Implementation, maintenance and documentation of computational
pipelines for analysis of DNA sequencing data
Sequencing data.
Meetings, presentations, seminars.

Requirements:

Education and Preferred Qualifications:

Position minimally requires a degree in program in Computer
Science, Bioinformatics, Computational Biology, Data Science or other related field.
Working experience in a related position preferred.

Candidates with a PhD are also being considered.

Candidate will be responsible for
planning, execution, analysis of study and communication with other groups involved in
study. Qualified candidates will have knowledge of Programing in Python, Bash, R, Julia
and experience with NGS data files including Bam, VCF and FASTQ. Experience in
designing multiplexed PCR assays, and ctDNA analysis recommended.

PM21

PI191509177
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