This job has expired

Associate Director, Mechanistic Biology, In Vivo Sciences

Employer
Calico LLC
Location
San Francisco, California, US
Salary
Competitive
Closing date
Sep 27, 2022

View more

You need to sign in or create an account to save a job.
We're explorers, optimists, scientists, engineers, technologists, drug developers and more, working together to make a difference in peoples' lives.

Calico is proud to be an equal opportunity workplace.

Please note: Calico does not contact people regarding jobs that are not listed on our Careers page and we only accept resumes submitted via Calicolabs.com under each job title. We do not use any online chat forums as a means to make initial contact with job applicants. If you believe you have received an unauthorized inquiry, please contact us at calico-security@calicolabs.com .

2022 Calico Life Sciences LLC. All rights reserved.

Associate Director, Mechanistic Biology, In Vivo Sciences at Calico South San Francisco, CA
Who we are:
Calico (Calico Life Sciences LLC) is an Alphabet-founded research and development company whose mission is to harness advanced technologies and model systems to increase our understanding of the biology that controls human aging. Calico will use that knowledge to devise interventions that enable people to lead longer and healthier lives.

Position Description:

Calico is seeking a highly motivated and innovative scientist skilled at non-clinical research and drug development. She/he should have demonstrated expertise and track record in conducting mechanistic investigations of translationally relevant (patho)physiological pathways in academia or industry. Broad knowledge of biological mechanisms coupled with intellectual agility and an ability to conduct hypothesis driven experiments that uncover deep mechanistic insight is a must. An interest in or experience working on pathways relevant to human aging or age related diseases will also be viewed very favorably. This person will establish a research group at Calico with 2-3 direct reports and work closely with discovery scientists, computational scientists, human geneticists, preclinical pharmacologists, and other members of the drug
development organization. The group will be primarily responsible for conducting late-stage research and generating key data that inform and enable program transitions within Calico's drug development portfolio. They are also expected to investigate, experimentally assess, and prioritize potentially broad indication spaces targeted by pleiotropic age-related pathways. This position provides exciting opportunities in translational medicine at Calico primarily through the generation of novel actionable insights into disease biology that can support programs across both research and development. Calico promotes collaborations and will provide access to advanced technologies and infrastructure in the areas of, for example, pre-clinical imaging, genomics, microscopy and biochemistry as well as advanced data analysis capabilities. This position will report to the Head of In Vivo Sciences.

Position responsibilities:
  • The qualified candidate will be responsible for establishing a research laboratory, hiring key personnel, and directing hypothesis driven non clinical research in support of Calico's pipeline projects.
  • This group will be responsible for delivering novel mechanistic insight into age-related (patho)physiological pathways of interest to Calico, identification of therapeutic opportunities for our late-stage research initiatives and validation of new targets.
  • She/he will work closely with Calico's basic research scientists, preclinical pharmacologists and R&D project teams to provide high-quality preclinical data necessary to enable decision making and advancement to early clinical development.
  • The candidate will have the opportunity to participate in the evaluation of new targets identified by our Business Development group and to develop strategies to validate these targets.
  • The candidate will be required to generate experimental plans, gain approval, execute studies and present study reports and recommendations to various governance forums in a matrixed environment.

Position requirements:
  • Applicants must have an PhD, or MD, PhD with broad experience in conducting translationally relevant non-clinical research and direct experience and understanding of biopharmaceuticals and drug development.
  • She/he must have a minimum of 5-8 years of industry or independent academic experience and a strong scientific track record as evident from publications, IND filings and/or patents.
  • Strong interpersonal and communication skills are required, and the candidate must be a team player with the ability to influence project direction in a cross functional team environment.
  • An interest in mechanisms of human aging or experience working on age-related diseases is a strong plus but not essential.
  • Must be willing to work onsite at least three days per week

Calico requires all new hires to be fully vaccinated for COVID-19 prior to the first date of employment. As required by applicable law, Calico will consider requests for Reasonable Accommodations.

Are you eligible to work in the United States?

Will you now or in the future require sponsorship for employment visa status (e.g., H-1B visa status)?

Education - School Attended

Highest Degree Earned

To submit your application, please read and consent to Calico's Privacy Policy. *

Calico's Privacy Policy

Voluntary Self-Identification

For government reporting purposes, we ask candidates to respond to the below self-identification survey. Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiring process or thereafter. Any information that you do provide will be recorded and maintained in a confidential file.

As set forth in Calico 's Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law.
Gender Are you Hispanic/Latino? Please identify your race Race & Ethnicity Definitions
If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection. As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measure the effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categories is as follows:

A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.

A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.

An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.

An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.
Veteran Status
Form CC-305

OMB Control Number 1250-0005

Expires 05/31/2023
Voluntary Self-Identification of DisabilityWhy are you being asked to complete this form?
We are a federal contractor or subcontractor required by law to provide equal employment opportunity to qualified people with disabilities. We are also required to measure our progress toward having at least 7% of our workforce be individuals with disabilities. To do this, we must ask applicants and employees if they have a disability or have ever had a disability. Because a person may become disabled at any time, we ask all of our employees to update their information at least every five years.

Identifying yourself as an individual with a disability is voluntary, and we hope that you will choose to do so. Your answer will be maintained confidentially and not be seen by selecting officials or anyone else involved in making personnel decisions. Completing the form will not negatively impact you in any way, regardless of whether you have self-identified in the past. For more information about this form or the equal employment obligations of federal contractors under Section 503 of the Rehabilitation Act, visit the U.S. Department of Labor's Office of Federal Contract Compliance Programs (OFCCP) website at www.dol.gov/ofccp .
How do you know if you have a disability?
You are considered to have a disability if you have a physical or mental impairment or medical condition that substantially limits a major life activity, or if you have a history or record of such an impairment or medical condition.

Disabilities include, but are not limited to:
  • Autism
  • Autoimmune disorder, for example, lupus, fibromyalgia, rheumatoid arthritis, or HIV/AIDS
  • Blind or low vision
  • Cancer
  • Cardiovascular or heart disease
  • Celiac disease
  • Cerebral palsy
  • Deaf or hard of hearing
  • Depression or anxiety
  • Diabetes
  • Epilepsy
  • Gastrointestinal disorders, for example, Crohn's Disease, or irritable bowel syndrome
  • Intellectual disability
  • Missing limbs or partially missing limbs
  • Nervous system condition for example, migraine headaches, Parkinson's disease, or Multiple sclerosis (MS)
  • Psychiatric condition, for example, bipolar disorder, schizophrenia, PTSD, or major depression
Disability Status
1 Section 503 of the Rehabilitation Act of 1973, as amended. For more information about this form or the equal employment obligations of Federal contractors, visit the U.S. Department of Labor's Office of Federal Contract Compliance Programs (OFCCP) website at www.dol.gov/ofccp .

PUBLIC BURDEN STATEMENT: According to the Paperwork Reduction Act of 1995 no persons are required to respond to a collection of information unless such collection displays a valid OMB control number. This survey should take about 5 minutes to complete.
You need to sign in or create an account to save a job.

Get job alerts

Create a job alert and receive personalized job recommendations straight to your inbox.

Create alert