Senior Scientist, Cancer Cell Biology

We are seeking an Senior Scientist, Cancer Cell Biology to join a biotech in Boston MA developing novel, first in class therapeutics for oncology and other diseases. The successful candidate will lead and drive efforts as part of a dynamic and collaborative cross-functional team supporting target identification, validation, and small molecule drug discovery for oncology targets. The ideal candidate will be an independent thinker with excellent communication skills who will provide insights towards experiment design and interpretation. The ideal candidate will have a track-record of project leadership, deep scientific rigor and drug discovery experience in oncology.

Responsibilities:

• Lead projects providing key insights, experimental design, execute and overseeing a diverse range of activities including target ID & validation, target prioritisation and develop cell-based assays for small molecule lead optimisation and mechanism of action studies.
• Work effectively with an interdisciplinary team of computational biologists, medicinal chemists and biochemists to advance lead asset programs.
• Design and implement biomarker assays, cellular functional assays, and establish PK/PD efficacy relationships in relevant cancer in vivo models.
• Interpret, summarise and present research findings to multidisciplinary project teams.
• Proactively review literature for latest scientific findings, ideas, and methods/technologies.

Requirements and Qualifications:

• PhD in Cell & Molecular Biology, Cancer Biology or related field plus experience in biotech or pharma (leveling will be commensurate with relevant years of industry experience).
• Experience contributing to and leading small molecule cancer drug discovery programs from discovery towards the clinic.
• Experience in novel target identification and progressing nominated targets to drug discovery projects
• Experience mentoring individuals or small teams in cancer cell biology.
• Proven success collaborating with interdisciplinary teams of computational biologists, medicinal chemists and biochemists.
• Success managing and coordinating teams (internal or external CROs).
• Experience in designing and implementing genetic or pharmacological screens using an image based readout is a plus.
• Outstanding oral presentation and written communication skills and a track record of publishing in peer-reviewed journals.

If you are having difficulty in applying or if you have any questions, please contact Danielle Bahnasy at (+1) 646-868-5142.

Proclinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies.

Proclinical Staffing is an equal opportunity employer.

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