Sr. Scientist/Principal, Discovery Biology

Surrozen is recruiting for a talented Senior/Principal Scientist in the Discovery Biology Department. The candidate will play a leading role in exploring Wnt signaling pathway in various disease areas, to identify lead molecules, to understand the mechanism of action of molecules, and to support clinical development of lead candidates. The successful candidate will be expected to independently design, execute and manage internal research projects, collaborate with other functional groups within the broader organization and manage external collaborations. In addition, the candidate will contribute to patent filings and publications and present research finding to various audiences including senior management. This position reports to the Head of Discovery Biology. The preferred candidate will bring enthusiasm, intellectual curiosity, scientific integrity, and a desire to understand biological principles of developing regenerative medicine therapeutics.
Responsibilities:

• Biochemical assay and cell-based assay development and validation
• Expression profiling to inform drug candidate profiles
• Target identification and validation
• In vitro pharmacology and in vitro model development and validation
• Mechanism of action studies
• Collaborate closely with a fully integrated team to make key decisions on program progression
• Implement and develop novel organoid culture systems for use in disease modeling

• PhD in Development Biology, Stem Cell Biology, Cell & Molecular Biology, Genetics or related disciplines
• Well versed in the latest cellular and molecular biology techniques
• Significant experience probing complex cellular signaling pathways
• Demonstrated scientific productivity as evidenced by a strong publication record in top tier journals

Who We Are
Surrozen is a biotechnology company focused on discovering and developing novel regenerative medicines with a focus on unlocking the powerful self-renewal properties of the body through specific control of the Wnt signaling pathway.

Our vision is to engage the body's own biological tissue repair mechanisms with our targeted regenerative antibodies, overcoming research and development hurdles that have been previously intractable, and have held back drug development efforts in the promising area of Wnt biology.

We are an Equal Opportunity Employer offering a competitive salary and benefits.