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Biologist

Employer
Equiliem
Location
Rockville, Maryland, US
Salary
Competitive
Closing date
Aug 9, 2022

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Sector
Academic / Research
Field
Conservation science
Discipline
Other
Salary Type
Salary
Employment Type
Full time
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The selected candidate will work as part of a multidisciplinary team of innovative scientists, using cutting-edge technologies including tissue biofabrication, tissue chips, quantitative cell imaging, histology, assay development, drug screening, data science and other 'omics' technologies (e.g., scRNAseq) to develop advanced 3-D cellular models to study viral infections and drug screening.
Minimum Education
Master's
Resume Max Pages
15
Certifications & Licenses
* Ph.D. in Virology, Biochemistry, Cell Biology, Molecular Biology or a related disci-pline. Three (3) years of specialized experience plus a Master's degree is equivalent to a Ph.D. Five (5) years of specialized experience plus a BA/BS degree is equivalent to a Ph.D.
* Minimum of five (5) years of related experience in Biosafety Level 2 or 3 (BSL3) re-search environment.
Skills (Ranked By Priority)
1. Biosafety Level 2 or 3 (BSL3) research environment.
2. Maintaining accurate and detailed records of laboratory experiments.
3. Strong communication skills, both oral and written.
4. Excellent analytical, organizational and time management skills.
5. Ability to multi-task, set priorities and pay close attention to detail.
1, 2, 3, 4, 5 _represents priority rankings, where 1 is highest priority and 5 is lowest priority of those ranked_
Software
* outlook
* powerpoint
* excel
Field of Study
* Biochemical Sciences
DELIVERABLES
* Work products and documents related to developing research plans and Research Collaborative Agreements; work with staff on grant/funding applications coauthored with NCATS colleagues and external collaborators. - Daily
* Work products and documents related to developing and optimizing cell-based and tis-sue-based infection models, including BSL2 and BSL3 viruses,; analyze experimental results; organize findings into tables and figures. - Daily
* Work products and documents related to evaluating new techniques and instruments; search literature; propose, design, and test alternative assays; confirm assay results; determine EC50/specificity; develop secondary assays. - Daily
* Work products and documents related to maintain and update notebooks and equipment; prepare technical reports, summaries, and manuscripts; prepare oral presentations and posters. - Daily
STATEMENT OF WORK DETAILS
functional responsibility
Provides technical experience needed to assist in studying the basic principles of plant and animal life
description
* Develop and maintain liaisons and effective working relations with groups and individuals, agencies, and the public to encourage cooperative management strategies or to develop information and interpret findings
description
* Work with the 3D TBL and Antiviral Program for Pandemics to establish a portfolio of complex physiologically relevant 3D tissue models as predictive screening platforms to study viral infections and drug testing
description
* Work as part of a multidisciplinary team of innovative scientists using cutting edge tech-nologies like tissue biofabrication, tissue chips, quantitative cell imaging, histology, assay development, drug screening, data science and other omics technologies including scRNAseq to develop advanced 3D cellular models to study viral infections and drug screening
description
* Develop and perform viral detection assays in a variety of tissue-based platforms
description
* Work with the Antiviral Program for Pandemics (APP) to establish a portfolio of high throughput, 96-, 384- and 1536-well live virus platforms for studying BSL2 and BSL3 viral infections in a variety of disease relevant models.
description
* Screen 384- and 1536-well live virus platforms for identifying antiviral compounds in APP priority viruses/viral families.
description
* Identify and move forward lead compounds for further antiviral compound development.
description
* Establish and maintain collaborations with both internal and external teams.
description
* Work with the biochemical, artificial intelligence, and chemistry teams at NCATS to identify and develop lead compounds for antiviral therapy.
description
* Work with high impact human viral families identified to have outbreak or pandemic potential.
description
* Work with biosafety level 2 and biosafety level 3 viruses.
description
* Work with Advanced Models and Cell Based Discovery Team to support efforts to gen-erate complex physiologically relevant 3D tissue models as predictive screening plat-forms to study viral infections and drug testing.
description
* Effectively prioritize, communicate, and understand projects and project impact.
description
* Work independently as well-trained problem solvers in virology.
functional responsibility
Assists with performing basic laboratory experiments and procedures
description
* Monitor and observe experiments, recording production and test data for evaluation by research personnel
description
* Analyze experimental data and interpret results to write reports and summaries of findings
description
* Develop research plans for new projects, including strategies for screens and advanced characterization in tissue models, including BSL2 and BSL3 viruses such as SARS-CoV-2
description
* Develop andor optimize tissue based assays, including the use of pathogenic viruses, for antiviral and antiviral disease panels
description
* Tissue culture, passaging, and plating
description
* Effectively communicate and present data.
description
* Keep accurate and complete records of all scientific experiments according to estab-lished procedures.
description
* Draft technical reports, manuscripts and patent applications.
description
* Present work to internal and external collaborators as needed.
description
* Work as part of a multidisciplinary team of innovative scientists using cutting edge technologies like tissue biofabrication, tissue chips, quantitative cell imaging, histology, assay development, drug screening, data science and other 'omics' technologies includ-ing scRNAseq to develop advanced 3D cellular models to study viral infections and drug screening.
description
* Work with team on the interpretation of assay outcomes.
description
* Analyze the experimental results and organize findings into tables and figures. probe development.
description
* Analyze and organize experimental results using data analysis/visualization software.
description
* Prepare oral presentations and posters for internal and external groups/conferences.
description
* Identify potential collaborators, academic, governmental, and industry; propose and in-vestigate new target projects for initiation based on novelty and relevance to human health.
functional responsibility
Prepares, organizes and maintains various lab samples, supplies, and equipment
description
* Operate laboratory equipment to analyze samples
description
* Analyze laboratory findings
5
functional responsibility
Learns new laboratory techniques and procedures
description
* Program and use computers to store, process, and analyze data
4
description
* Monitor operational procedures in technical environments to ensure conformance to standards
3
description
* Interpret research or operational data
2
description
* Record research or operational data
1
1, 2, 3, 4, 5 _represents priority rankings, where 1 is highest priority and 5 is lowest priority of those ranked_
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