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Biologist III

Employer
KYYBA, Inc
Location
Worcester County, Massachusetts, US
Salary
Competitive
Closing date
Jul 4, 2022

View more

Sector
Academic / Research, Consultancy/Private Sector
Field
Conservation science
Discipline
Other
Salary Type
Salary
Employment Type
Full time
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Job Description

Biologist III/IV- Client Platform Biology

Description

has an opening for an Biologist III/IV contract position within the Antibody Drug Conjugate (Client) Platform Team at our Bioresearch Center in Worcester, MA. The Client group within DDST collaborates with drug discovery project teams across all therapeutic areas including Oncology and Immunology. The ideal candidate will effectively work to collaborate with chemists, biologists and pharmacologists to characterize large and small molecules for Client development.

Key Responsibilities:

• Design, optimize, and execute high content cellular imaging assays using genomic manipulations techniques, small or large molecules to study cellular trafficking and pathway biology

o Practical experience with designing and executing cellular assays on high content imaging platforms, data analysis and visualization

o Excellent computer skills and a good understanding of basic image analysis software

• Experienced with working with 2D and 3D in-vitro model systems

o Experienced with low and HTS screening methods

o Experience with designing Co-Culture model systems

• Experienced with liquid handling automation systems

• Experienced with trouble shooting in-vitro assays and validating in-vitro assays

o Experienced with protocol write-ups

• Experienced with corelating target modulation with phenotype while screening or characterizing large or small molecules

• Work collaboratively with project teams to deliver targets across portfolio

• Demonstrate scientific excellence, work ethic, and dedication to team and project goals

• Work collaboratively in a matrix with project teams and members of the Biologics Group to drive innovation and deliver Client therapies to patients

• Develop productive collaborations and communication with other groups across therapeutic areas

Basic Qualifications:

• Bachelor's degree in related discipline with 5 or more years of experience and a BS/MS in Biology or Biochemistry

• Experienced screening large and small molecules (reporter assays, proliferation and cytokine release)

• Experience executing antibody internalization experiments is a plus

• Experience with transfections and generating transient and stable cell lines

• Experience culturing adherent, suspension and primary cells

• Proficiency in performing flow cytometry and ELISA experiments

• Experience with performing qPCR and automated western blot analysis

• Experience working with high throughput laboratory workflows and instruments such MACsQuant, FACS Canto, Microbeta, Wes, ImageXpress confocal, Amnis Imagestream, Via7 (taqman) and Spectramax plate readers.

• Experience documenting experimental methods and results into BIOELN

• Ability to summarize and present results to project teams

MUST HAVE:

• MS in related discipline

- 3 -5 years industry/lab experience

- High Content Imaging (Florescent Microscopy, Cellular Staining, Imaging analysis etc.)

NICE TO HAVE / NOT REQUIRED:

- Cell Line Development

- Loss/Gain function

- Screen genetic modifiers

Max

Significant Work Activities and Conditions Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8 hour day)

About Kyyba:

Founded in 1998 and headquartered in Farmington Hills, MI, Kyyba has a global presence delivering high-quality resources and top-notch recruiting services, enabling businesses to effectively respond to organizational changes and technological advances.

At Kyyba, the overall well-being of our employees and their families is important to us. We are proud of our work culture which embodies our core values; incorporating value, passion, excellence, empowerment, and happiness, creates a vibrant and productive atmosphere. We empower our employees with the resources, incentives, and flexibility that they need to support a healthy, balanced, and fulfilling career by providing many valuable benefits and a balanced compensation structure combined with career development.

Disclaimer:

Kyyba is an Equal Opportunity Employer.

Kyyba does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, non-disqualifying physical or mental disability, national origin, veteran status or any other basis covered by appropriate law. Minorities / Females / Protected Veterans / Individuals with Disabilities are encouraged to apply. All employment is decided on the basis of qualifications, merit, and business need.

Rewards:

Medical, dental, vision

401k

Term life

Voluntary life and disability insurance

Optional Pre-paid legal plan

Optional Identity theft plan

Optional Medical and dependent FSA

Work-visa sponsorship

Opportunity for advancement

Long-term assignment with opportunity for hire by client

SELECT AWARDS

An INC 5000 company for 10 years

Corp! Michigan Economic Bright Spots

Crain's Detroit Business Top Staffing Service Companies in Detroit

TechServe Alliance Excellence Award- IT and Engineering Staffing & Solutions

Best of MichBusiness winner in HR Wizards & Partnerships

Metro Detroit Elite Category: Recruitment, Selection & Orientation for 101 Best & Brightest

101 Best & Brightest Companies to Work for in Michigan
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