At Bristol Myers Squibb, we are inspired by a single vision - transforming patients' lives through science. In oncology, hematology, immunology and cardiovascular disease - and one of the most diverse and promising pipelines in the industry - each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.
The Tumor Microenvironment Thematic Research Center (TME TRC) is focused on developing therapeutic targets at the intersection of tumor, stromal and immune biology within the TME with the goal of enhancing responsiveness to checkpoint blockade and targeted therapiesand transforming response and durability rates for cancer patients. Comprising of scientists across multiple disciplines we are responsible for the biology and translational science necessary to support drug development from target identification through to first in human studies.Position Summary:
The Lymphoid Biology group is seeking a highly motivated Research Scientist to join the Immunology and Stromal Biology Discovery group and aide in the advancement of therapeutic targets in drug discovery and early development. The candidate will work collaboratively with drug discovery, predictive science, translational and clinical teams to support the selection and advancement of clinical candidates including early target discovery, validation, and mechanism of action studies. The successful candidate will be heavily involved in the design, execution and analysis of in vitro assays and in vivo efficacy studies in mouse tumor models. Strong technical skills with a background in cancer immunology and lymphoid biology is desired.Core Responsibilities:
- Design and execute experimental plans that support project progression across non-clinical and clinical milestones
- Conceptualize, design, and perform novel functional assays that contribute to target validation, drug lead selection, or mechanism of action
- Present experiments and results at project team meetings, group meetings, and company meetings
- Analyzing current scientific literature to help identify new targets or new strategies for existing targets
- Advance group capabilities and know-how by identifying and implementing novel technologies
- Provide mentorship of junior colleagues in the group
- B.S. with 5-10 years of relevant experience, M.S. with 2-7 years of relevant experience, or PhD with 1-4 years of experience in molecular/cell biology, immunology or related field is required
- Industry experience in drug discovery or translational research is a plus
- Experience with multi-color flow cytometry is required
- Experience in isolation, characterization and functional assay development using primary cells of rodent and/or human origin is desired
- Able to interpret and summarize scientific data in a clear and concise manner
- Understanding of, and experience in assay development related to lymphoid cells and the tumor microenvironment a plus
- Excellent interpersonal skills with the ability to work both independently and collaboratively in a dynamic and innovative research environment
- Flexibility and interest in learning new techniques and skills in accordance with the research program needs
- Detail-oriented, with excellent organizational, and record-keeping skills
Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.
Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture.
To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.
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