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Associate Scientist - Platform Biology

Employer
Cyteir Therapeutics
Location
Lexington, Massachusetts, US
Salary
Competitive
Closing date
Jun 28, 2022

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Sector
Academic / Research
Field
Conservation science
Discipline
Biology
Salary Type
Salary
Employment Type
Full time
Cyteir Therapeutics seeks an enthusiastic and capable Research Associate to join the Platform Biology team to help develop and implement our research portfolio. This Associate Scientist will be a key contributor to our preclinical research efforts to identify novel small-molecule DNA repair inhibitors for the treatment of cancer. The ideal candidate will have experience in cellular and molecular biology techniques and mammalian tissue culture, with a track record of significant contributions to past research efforts. Expertise in the arena of cancer biology is a plus but not required.

Job Responsibilities:

· Validate and execute cell-based assays to identify and characterize drug candidates in our preclinical pipeline of DNA repair-targeting small molecules

· Perform a variety of standard molecular and cellular lab techniques and help implement novel assays to better understand how our drug candidates are impacting cell survival/stress, metabolic, or DNA damage repair pathways

· Maintain mammalian cell lines in tissue culture

· Work collaboratively within our multi-disciplinary team of scientists

· Maintain familiarity with advancements in the field and new lab techniques and technologies

· Maintain accurate, well-organized experimental records (written and ELN)

· Organize and present experimental results at weekly group meetings

Job Qualifications:

· BA/BSc or MSc in biological sciences with 0-2 years of relevant hands-on lab experience

· Experience with aseptic techniques fundamental to mammalian tissue culture required

· Experience with cell biology extraction techniques (protein, nucleic acids) required

· Experience with cell biology techniques preferred (transfection, transduction, microscopy, IF)

· Experience in basic molecular biology methods (PCR, qPCR, restriction digest, cloning) and biochemical methods (immunoblotting, etc) preferred

· Experience with HTS, image analysis, and automation would be appreciated

· Flexible approach to drug discovery problem solving expecting collaboration across groups

· Well organized and able to maintain detailed records of experimental work

· Ability to communicate clearly in an open, timely manner

· The courage to say "I don't know" or "I made an error" and ask for help

· A sense of adventure and excitement - experience a collaborative and dynamic work culture in a small and growing company

· Passionate about challenging health issues and perseverance in problem solving

· Desire to learn and to grow both personally and professionally in advancement of a career in biomedical research and drug discovery

COVID vaccine and booster is required

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