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Senior Research Scientist, Platform Biology

Siduma Therapeutics
New Haven County, Connecticut, US
Closing date
Jun 28, 2022

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Academic / Research
Conservation science
Salary Type
Employment Type
Full time
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Please Note: Documentation of COVID vaccination consistent with current CDC and FDA guidelines is required for all employees of SIDUMA.

About Siduma

Siduma Therapeutics, founded by innovator Dr. Craig Crews, is leveraging extensive heterobifunctional molecule expertise to build a new, disruptive therapeutic platform targeting disease causing proteins. Siduma has assembled an exceptional leadership team and board with deep expertise in platform and drug development as well as company building. The company has recently closed a series A financing round with industry-leading investors. Qualified candidates seeking a highly mission-driven and collaborative culture along with cutting edge science are encouraged to apply for our open roles.

Primary Responsibilities:
  • To design and leverage assays from cell biology, biophysics, biochemistry and other fields as required to develop an understanding of the mechanistic details underpinning the Siduma platform.
  • To robustly characterize and rapidly deploy the learnings of the Siduma platform mechanism(s) to demonstrate proof-of-concept in vitro against multiple therapeutic targets.
  • To deploy cell biology and biochemistry expertise as required to design and execute on a series of complex experiments, protocols, and procedures in support of stated platform and project goals including supporting the progression of projects to IND.
  • To independently analyze and interpret results and identify and solve problems, using technology- and target-specific controls to characterize methods and provide context.
  • To effectively and concisely present data, conclusions and recommendations at platform, project and/or functional unit meetings.
  • Contribute to effective day-to-day lab management and operations as part of lab team. May have supervisory responsibilities.

  • Candidates should have a PhD in cell biology, biophysics, biochemistry, or a related field with postdoc training experience.
  • Candidate with industry experience is highly preferred and being familiar with multi-well plate format for cell-based drug screening is a plus. Solid understanding of principles of multiple cellular and biochemical assay technologies with corresponding hands-on experience. The candidate should demonstrate strong assay development skills including medium- and high-throughput methods.
  • A rigorous experimental mindset coupled with scientific curiosity and a results-driven approach.
  • Strong interpersonal skills, and strengths in verbal and written communication are important for success. Experience presenting to a diverse audience.
  • Team player capable of operating effectively in a fast-paced biotech startup environment. We seek a quick learner who plans and executes research aligned to management priorities. Engages in appropriate risk-taking and work prioritization with direction and guidance from management.
  • A demonstrated ability to think logically and critically. Ability to make progress on multiple projects simultaneously and aligned company priorities and focus.
  • Works independently, safely, and productively in the laboratory.
  • Shows accountability for meeting corporate, functional department or project objectives in addition to personal job performance goals and those of any subordinates.
  • Meticulous record keeping, proficiency with Microsoft Office and familiarity with data analysis software, such as GraphPad Prism.

Siduma is an Equal Opportunity Employer. Principals only.
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