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Associate Principal / Senior Scientist, Cancer Biology

Employer
LifeMine Therapeutics
Location
Cambridge, Massachusetts, US
Salary
Competitive
Closing date
Jun 28, 2022

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Sector
Academic / Research
Field
Conservation science
Discipline
Biology
Salary Type
Salary
Employment Type
Full time
LifeMine Therapeutics is reinventing drug discovery by mining fungal biodiversity to develop novel therapeutics to address previously intractable therapeutic challenges. Through its drug discovery engine and proprietary fungal strain collections, LifeMine has discovered, in the genomic space, hundreds of potentially high-impact drug candidates relevant to targets across all major disease areas. With operations in Cambridge and Gloucester, Massachusetts, LifeMine's initial focus is on highly impactful medicines in oncology and immune modulation.

Job Summary

Located in Cambridge, MA, we are seeking a highly motivated Associate Principal / Senior Scientist to join our growing Cancer Biology team, with the unique opportunity to strategically influence LifeMine's drug discovery programs . The ideal candidate will have made substantial contributions to drug discovery efforts in the oncology space, including involvement in significant assay development.

Job Responsibilities
  • Develop and execute approaches to evaluate drug activity, mechanism, and translatability; design and execute experiments; accurately record, analyze, and present data to the project team and other stakeholders
  • Influence LifeMine's drug target selection and evaluation process
  • Develop and run assays to address key questions and drive the drug discovery process
  • Collaborate across functional teams to efficiently identify drug candidates and move them to the clinic
  • Maintain relationships with external CROs to support our research goals


Job Requirements
  • PhD. in Biology, Biochemistry, or Pharmacology with 3+ years of drug discovery experience in oncology programs
  • Demonstrated track record of providing significant biological insights to drug discovery efforts in a Biotech Industry setting, especially in the areas of oncology and cell signaling
  • Expertise in cellular and molecular biology techniques including mammalian cell culture, flow cytometry, qPCR, Western blotting, and microscopy
  • Experience optimizing and developing medium- to high-throughput cell-based mechanistic and in vitro/ex vivo functional assays
  • Familiarity with state-of-the-art cell assay technologies e.g. AlphaLISA, HTRF, MSD, In-Cell Western, etc.
  • Excellent problem-solving, multi-tasking, organizational, and communication skills
  • Ability to work independently and collaborate in a fast-paced team environment


LifeMine is an Equal Opportunity Employer and Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sexual orientation, gender identity, age, physical or mental disability, veteran status, genetic information, ethnicity, citizenship, or any other characteristic protected by law.

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