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Scientist I Precision Medicine Translational Research Molecular Biology

Employer
AbbVie
Location
Worcester County, Massachusetts, US
Salary
Competitive
Closing date
Jul 1, 2022

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Sector
Academic / Research
Field
Conservation science
Discipline
Biology
Salary Type
Salary
Employment Type
Full time
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The Precision Medicine Department is committed to advancing drug development and patient care through building a deeper understanding of disease biology and developing tools to optimize clinical decision making and customize treatment for patients. The Scientist will be part of a fast paced and multi-disciplinary team responsible for developing and implementing new technologies to enable decision making in clinical trials, and evaluate disease and drug biology. The successful candidate will have a demonstrated ability to design, execute, troubleshoot, and interpret experiments independently. The successful candidate will have expertise in advanced molecular techniques such as next generation sequencing and instrument automation. The successful candidate will also have experience with handling human tissues and samples, and developing assays to evaluate drug target engagement, receptor occupancy and pharmacodynamics, and interrogate disease and drug biology.
Key Responsibilities:
Maintain a high level of productivity in the laboratory
Independently design, execute, and interpret critical experiments to answer scientific questions
Demonstrate the ability to resolve project hurdles by utilizing available information and technical expertise in molecular biology
Analyze and document results, placing data in proper scientific context through review of relevant literature and report findings at team meetings
Understand and adhere to corporate standards regarding code of conduct, safety, controlled drugs and radioactive compounds
Qualifications:
Bachelor's Degree or equivalent education and typically 2+ years of experience, Master's Degree or equivalent education and typically 0years of experience
Experienced in RNA isolation, qPCR, and RNAseq
Experience working with human tissues
Experience with scRNA-seq or CITE-seq, or instrument automation for library preparation (Beckman Biomek i7) is a plus
Knowledge of target engagement, receptor occupancy and pharmacodynamic assay development is a plus
Knowledge of basic immunology concepts
Ability to work with multidisciplinary groups in a fast-paced discovery team setting
Effectively communicate cross-functionally with team members throughout the organization
Demonstrated ability to communicate effectively (both written and oral)
Equal Opportunity Employer Minorities/Women/Veterans/Disabled
Additional Information:
Travel: No
Job Type: Experienced
Schedule: Full-time
PDN-ABV2115297
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