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Senior Associate Scientist, in vivo Biology

Employer
Ensoma
Location
Boston, Massachusetts, US
Salary
Competitive
Closing date
May 31, 2022

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Sector
Academic / Research
Field
Conservation science
Discipline
Biology
Salary Type
Salary
Employment Type
Full time
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Imagine a world where debilitating diseases can be cured through a one-time treatment regardless of a person's geographic location, closing the gap on the healthcare disparities that discriminate against those without access to a cure for their disease.
Imagine you are an instrumental member of an unstoppable, collaborative team that challenges the status quo to make things happen and are supported by a company culture that holds trust, authenticity, and team member development at its center to ensure the focus is on patients who are waiting for therapy.
We are seeking an independent and highly motivated Senior Associate Scientist to join our research and development team to conduct complex studies using animal models and ex vivo sample analysis to support development of novel therapeutics. In this role you will possess strong in vivo technical skills and a solid understanding of disease animal models in hematology/immunology field.
You will join a team of scientists dedicated to moving a novel gene therapy drug candidate into the clinic . Join us and be part of building a company revolutionizing the reach and access of the curative power of genomic medicines for patients with serious diseases.
Responsibilities:
  • Conduct complex in vivo experiments using disease and immunocompromised mouse models.
  • Perform primary cell isolation and culture.
  • Execute in vitro and ex vivo cell-based assays.
  • Manage internal and external mouse colonies.
  • Analyze data and present results at group meetings and conferences.
  • Contribute to publications and written reports for regulatory filings.
  • Maintain laboratory equipment and rooms as required.
Qualifications:
  • B.S. in biological science with 6+ years or M.S. with 3+ years of academic and/or industry experience.
  • Experience in rodent handling dosing (IV, IP, IM, SC) and tissue collection, particularly of hemato-lymphoid organs (bone marrow, spleen, blood) is required.
  • Demonstrated experience in performing primary cell cultures, hematopoietic stem cell and/or immune cell based in vitro and in vivo assays (bone marrow transplantation)
  • Demonstrated experience in erythroid cell biology is a plus
  • Experience with multi-color flow cytometry and ability to operate flow cytometers independently are required.
  • Experience in gene therapy is a plus.
  • Hands on Nonhuman Primate HSC is a plus.
  • Ability to design experiments and troubleshoot technical hurdles independently.
  • Strong communication skills and willingness to learn and ability to adapt quickly in a fast-paced environment.
About Ensoma:
Ensoma believes the future of medicine lies within us. Our Engenious platform is the first to precisely engineer any or all hematopoietic and immune cells with a one-time, off-the-shelf in vivo treatment. Engenious therapies have an unmatched capacity to deliver all modern genetic modification tools and set a new standard for versatile cell programming and control across a range of complex diseases. Ensoma is supported by top-tier investors, a strategic collaboration with Takeda and a passionate team committed to a bold global vision for genomic medicine. Ensoma is based in Boston, Massachusetts. For more information, please visit www.ensoma.com.
About Ensoma:
Ensoma believes the future of medicine lies within us. Our Engenious platform is the first to precisely engineer any or all hematopoietic and immune cells with a one-time, off-the-shelf in vivo treatment. Engenious therapies have an unmatched capacity to deliver all modern genetic modification tools and set a new standard for versatile cell programming and control across a range of complex diseases. Ensoma is supported by top-tier investors, a strategic collaboration with Takeda and a passionate team committed to a bold global vision for genomic medicine. Ensoma is based in Boston, Massachusetts. For more information, please visit www.ensoma.com.
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