Biologist

Employer
Rangam Consultants Inc.
Location
Cambridge, Massachusetts, US
Salary
Competitive
Closing date
May 29, 2022

View more

Sector
Academic / Research, Consultancy/Private Sector
Field
Informatics / GIS
Discipline
Other
Salary Type
Salary
Employment Type
Full time
  • Looking for a Bench scientist
  • Intermediate level
  • 4 yrs exp needed in cellular assay
  • 100% onsite
  • Running western blot, qPCR, ELISA
  • Some exp in running immune based assay (Flow cytometry
  • Having exp with small molecule is needed
  • Able to analyze data
  • PhD will be considered
Description:
  • The candidate in this position will be responsible for developing and performing immune cell-based assays to enable oncology drug discovery programs.
  • The candidate will collect and analyze data and will be responsible for effectively communicating results to project teams.
  • The candidate should have strong communication and assay development skills and working knowledge of appropriate immuno-oncology cellular signaling assays.
  • A solid skill-set in qPCR, ELISA/Western Blot/MSD, flow cytometry, cell culture techniques, including experience handling primary cells and ex vivo samples for assay execution is strongly desired.
  • This position is 100% laboratory based.

Duties/Responsibilities:
  • Collaborate with colleagues in the larger group to develop high-quality cell-based assays
  • Adapt these assays for high-throughput formats
  • Execute routine cell-based screening assays to ensure rapid and high-quality data delivery
  • Analyze, interpret, and effectively report data at team meetings
  • Troubleshoot assays to ensure high quality control
  • Interface closely with colleagues to ensure assays and screening efforts are aligned to the scientific project goals
  • Interface with Informatics and automation colleagues proactively to drive the evolution of screening platforms and ensure adequate maintenance of the cell-based assay infrastructure

Key Experiences and qualities:
  • Experience with immune-based assays including: Isolation of immune-cell subsets, evaluation of lymphoid and myeloid cell biology and functional readouts, and tumor: immune cell co-cultures.
  • Demonstrated hands-on experience in developing various functional cell-based signaling assays (eg. Western blotting, Luminex, ELISA, MSD etc.) in recombinant and primary cells
  • Expertise in databases, data analysis & analytics and specialized analysis tools is required
  • Experience with automated liquid handlers, plate readers, software and robotics preferred
  • Flow cytometry experience is highly desired
  • Self-motivated and a proven ability to work in a multifunctional team setting
  • Detail-oriented, highly organized with the ability to run multiple interleafed projects
  • Excellent interpersonal and communication skills
  • Ability and desire to master new skills, methods and technologies that enhance departmental capabilities

Qualifications
  • BS or MS degree in biochemistry, pharmacology, cell biology or related field
  • 4+ years of relevant industry research experience in assay development & execution, preferably in a drug discovery setting

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