Senior Researcher, Biology

Title: Senior Researcher, Biology
Location: Cambridge, MA
Start date: ASAP
Responsibilities:

• We are seeking a motivated Senior Researcher with cell biology, biochemistry, and image analysis experience to join the Immunodementia Biology group at G2D2 in Cambridge, MA.
• The selected candidate will join a team working to assess the effects of glial modulation on Alzheimer's disease pathophysiology.
• Activities will involve a combination of in-vitro and in-vivo methods.
• The successful candidate will contribute to the execution of in-vitro and ex-vivo cell based assays to support the validation of targets to treat Alzheimer's disease.
• Primary responsibilities:
  • Work with Scientist to design, execute, and interpret experimental findings
  • Support in-vitro studies by participating in the development and execution of cell based assays
  • Support efforts to develop disease relevant cellular models using neurons and glia
  • Support in-vivo studies by participating in tissue dissociations and follow up biochemical and flow cytometry based assays
  • Communicate critical results and troubleshooting to the team
  • Maintain lab notebook and document data

Requirements:

• MS in biological sciences or BS in biological sciences with 2-3 years relevant experience in academia or industry
• Understanding of basic neurobiology
• A combination of the following skills
  • Experience with mammalian cell culture
  • Experience with immunofluorescence staining of cells and tissues
  • Experience with high content imaging and analysis
  • Experience with flow cytometry
  • Experience with western blot or ELISA techniques
  • Experience with tissue dissociation and cell isolation methods
  • A willingness to learn and adapt to new technologies as needed
  • An ability to adapt and respond to changes in a fast paced, collaborative environment
  • Excellent organizational and time management skills
    

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