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Scientist I, Biology

Employer
Planet Pharma
Location
Indianapolis, Indiana, US
Salary
Competitive
Closing date
Jan 27, 2022

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Sector
Academic / Research
Field
Conservation science
Discipline
Biology
Salary Type
Salary
Employment Type
Full time
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Duties: The biology scientist will have experience interrogating cellular and molecular mechanisms as they relate to kinase target pathway modulation, off-target liabilities and resistance. The candidates primary role will be lab based and include cellular assays to support drug discovery efforts. This position offers the opportunity to impact a growing portfolio of targeted therapies in a fast-paced and innovative research environment.

Responsibilities:
  • Independently conduct, optimize and proactively troubleshoot cellular screening assays.
  • Responsible for running cellular assays to screen small molecules, target validation and to establish PKPD relationships.
  • Employ cellular and molecular assays such as isolation of RNA, PCR, Western blotting, ELISA, and flow cytometry to dissect mechanism of action of small molecules.
  • Timely analyze and record detailed experimental data in an electronic laboratory notebook
  • Actively participate in cross-functional projects.
  • Present data to integrated project teams

Requirements:
  • BS/MS in cellular molecular biology, cancer biology or related discipline with 1-3 years of laboratory experience in industry or academic setting.
  • Experience in cell-based assays and mammalian cell culture, including transfection and transduction techniques, as well as stable cell line generation
  • Familiar with state-of-the-art experimental techniques and the ability to implement new technologies when applicable
  • Strong organizational and communication skills
  • Strong problem solving and interpersonal skills to facilitate cross-functional collaboration
  • Highly self-motivated , team player, capable of adapt to fast-paced and collaborative work environment
  • Previous drug discovery experience in cancer biology and immunology is a plus
  • Hands-on experience with MSD, AphaLISA , HTRF and Nanostring assay platforms is also a plus
  • Prior experience with automation, plate-based assays and HTS is a plus
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