At Bristol Myers Squibb, we are inspired by a single vision - transforming patients' lives through science. In oncology, hematology, immunology and cardiovascular disease - and one of the most diverse and promising pipelines in the industry - each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.
The Tumor Microenvironment Thematic Research Center (TME TRC) at Bristol Myers Squibb is focused on developing therapeutics at the intersection of tumor, stromal and immune biology with the goal of enhancing responsiveness to immune checkpoint blockade, targeted and cell therapies. Comprised of scientists across multiple disciplines, we are responsible for the biology and translational science required to support drug development from target identification through proof-of-concept (POC) studies in cancer patients.Position Summary:
We are seeking a highly motivated and experienced Scientist/Senior Scientist in cellular and molecular immunology who can provide technical leadership in designing and conducting experiments to drive advancement of early therapeutic targets as well as supporting drug development for cancer immunotherapy specifically in the areas of innate and adaptive tumor biology. The individual will be part of a dynamic and matrixed research team responsible for supporting all aspects of drug discovery and development.
This position will have an emphasis on generating relevant data for selection of clinical candidates and will also include early target discovery, validation, and mechanism of action studies for preclinical and clinical development. The successful candidate will be heavily involved in the design, execution and analysis of in vitro and in vivo efficacy studies in mouse tumor models. In addition, the successful candidate will perform various functional immunoassays to screen and characterize therapeutic candidates of both large and small molecule formats and work with cell lines and freshly isolated human tissue and blood cells.Core Responsibilities:
- Designing and executing experiments using murine and human primary immune cells
- Developing novel assays to characterize activity of candidate therapeutics
- Immune profiling of cultured immune cells, lymph tissues and tumor infiltrating leukocytes using multi-parametric FACS
- Analyzing and presenting scientific results to team meetings
- Working in a collaborative team environment
- Potentially include managerial responsibilities for 1-2 junior RAs depending upon prior experience
- PhD with 2+ years of postdoctoral or industry experience in the fields of immunology, oncology, molecular biology or biochemistry
- BS/MS with 5+ years of work experience in immunology and/or immuno-oncology
- Expertise in cellular and molecular immunology and functional assay development
- Extensive experience in multi-parametric flow cytometry
- Familiarity with in vivo models of immune disease or oncology
- Proficiency in scientific computer programs including Microsoft Excel, GraphPad, Spotfire, FlowJo
Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.
Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture.
To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.
Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application or if you are applying to a role based in the U.S. or Puerto Rico and you believe that you are unable to receive a COVID-19 vaccine due to a medical condition or sincerely held religious belief, during or any part of the recruitment process, please direct your inquiries to email@example.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.
Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.