The Associate Scientist works independently to perform and interpret in vitro cellular functional assays using primary cells and a variety of cell lines to answer specific biological hypotheses, identify and characterize antibodies using in vitro screening methodologies, organize functional activities for multiple assignments efficiently and productively, and present findings in larger team meetings. Essential Functions
RequirementsQualificationsEducation & Experience:
- Develops, optimizes and performs
- New methods and technologies for antibody discovery to specific targets, including established cell lines and primary cell-based assays.
- ELISA, MSD, flow cytometry, and in vitro cellular functional assays to characterize antibodies in support of discovery programs.
- Applies scientific literature to solve problems and formulate new ideas.
- Analyzes and interprets experimental results and make recommendations for next steps/further research.
- Organizes, summarizes and clearly presents data at project team meetings, group meetings and to senior management when appropriate.
- Prepares experimental write-ups for protocols, research reports, patent applications and manuscripts.
- Mentors and trains junior team members, providing scientific and technical expertise as necessary.
- Bachelors' degree in a biology-related discipline with a minimum of 10 years of related laboratory experience, or Master's in a biology-related discipline with a minimum of 8 years of related laboratory research experience
- Functional knowledge of, and working experience in, cell biology methodologies and cellular immunology, including mammalian cell culture, cell transfection, functional in vitro assays, ELISA, MSD, Luminex, and other multiplex systems including flow cytometry.
- Expertise in primary immune cell assays, such as T, B, NK, DC, and/or monocytes.
- Experience in primary mouse, cynomolgus monkey, and human lymphocyte and mononuclear cell purification and functional assays.
- Proficiency in basic computer data analysis and presentation applications, Microsoft Word, Excel, PowerPoint, GraphPad PRISM.
- Able to work with limited supervision, and effectively within a team setting, and design experiments to answer specific scientific questions.
- Able to learn new laboratory techniques efficiently, troubleshoot experiments, and ensure experiments are well designed and performed to a high standard.
- Able to author research protocols and provide ongoing input for assays transferred to external investigators or CROs in support of advancing the research portfolio into early clinical development.
- Ability to communicate clearly, and to report and present experimental results and analysis to supervisor, department colleagues, and at project team meetings.
- Effective interpersonal skills, including both written and oral communication skills.
- Team player with the ability to work effectively with AnaptysBio colleagues, intensely committed to success and getting the job done well in a highly dynamic environment.
- Ability to organize assignments and work within schedules and deadlines.
- Ability to multitask, prioritize, and function in a fast-paced entrepreneurial environment.
- Ability to work independently while also willing to follow protocols.
- Strong analytical and organizational skills.
- Highly attentive to details.
The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
While performing the duties of this job, the employee is regularly required to sit and talk or hear.
The employee frequently is required to use hands to finger, handle, or feel. The employee is occasionally required to stand, walk, and reach with hands and arms.
The employee must occasionally lift and/or move up to 10 pounds. Specific vision abilities required by this job include close vision and ability to adjust focus in order to read.Work Environment:
The work environment characteristics are representative of those an employee encounters while performing the essential functions of this job, typically in an open office environment. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
The noise level in the work environment is usually moderate. This position requires working with biological and/or chemical hazards.
All qualified applicants will receive consideration for employment without regard to race, color, sex, sexual orientation, gender identity, religion, national origin, disability, veteran status, age, marital status, pregnancy, genetic information, or other legally protected status.