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Research Assistant (Immunobiology)

Employer
Joslin Diabetes
Location
Boston, Massachusetts, US
Salary
Competitive
Closing date
Jan 23, 2022

View more

Sector
Academic / Research
Field
Informatics / GIS
Discipline
Modeling, Biology
Salary Type
Salary
Employment Type
Fellowship
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Overview:

We are seeking a highly motivated, bright and organized individual to join our lab to conduct translational research studies on the immune mechanisms underlying the development of premature cardiovascular disease in type 1 diabetes. The specific project involves use of both humanized mouse models and patient samples. Our research combines cutting-edge molecular and cellular immunology techniques, including flow cytometry, high-throughput human immunoassays, bioinformatics, and animal modeling.

The Research Assistant will be supervised, but will be expected to organize work flow and perform experiments independently. Responsibilities will also include transgenic mouse colony maintenance and assisting with general lab organization.

COVID VACCINE INFORMATION, PLEASE READ:

Along with our fellow health care organizations in the Longwood Medical Area and Greater Boston, all members of the Joslin workforce will be required to receive a COVID vaccine. The vaccine requirement holds true for Joslin employees who work fully remote and will be a condition of employment for all moving forward.

Therefore, the successful candidate would have to provide proof of full vaccination.

Responsibilities:

Isolate cells from human and mouse tissue or blood samples.

Perform cell staining for analysis by flow cytometry, cell sorting, or molecular analyses.

Assist in performing immunoassays including ELISA.

Culture different cell types using sterile techniques and perform functional assays

Assist with animal husbandry (setting up breeders, weaning pups, genotyping progeny). Maintain accurate, detailed, and up-to-date records and manage replacement of breeding animals to ensure propagation of the lines.

Report on progress of work in laboratory meetings.

Maintain accurate, detailed, and up-to-date electronic records of all procedures performed and results obtained; assist with the maintenance of databases.

Prepare laboratory reagents and assist with equipment maintenance.

Place orders for supplies as needed and assist with general lab organization.

Ensure safe laboratory practices and compliance with institutional research guidelines.

Other duties as assigned.

Qualifications:

B.S. in Biology or Biochemistry or related discipline

Minimum 1 year of hands-on laboratory experience, particularly working with animals and/or in molecular biology/immunology. Observational laboratory work undertaken as part of an introductory college course is insufficient.

Demonstrated competence with databases/spreadsheets and software packages

Must possess strong organizational skills

Ability to communicate information clearly in both oral and written form

Recognize and prioritize responsibilities

Work independently and collaboratively

Willing to work with mouse models
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