This job has expired

Principal Scientist, Myeloid Biology

Employer
Yoh, A Day & Zimmermann Company
Location
San Francisco, California, US
Salary
Competitive
Closing date
Jan 25, 2022

View more

Sector
Academic / Research
Field
Conservation science
Discipline
Biology
Salary Type
Salary
Employment Type
Full time
You need to sign in or create an account to save a job.
Yoh is seeking a Senior/Principal Scientist of Myeloid Biology to support our Clinical Stage Immuno-Oncology client in the San Francisco Bay Area. The Senior/Principal Scientist will be responsible for developing systems to interrogate myeloid cell-mediated regulation of tumor growth and evaluate myeloid-targeting strategies for anti-cancer treatment. This position calls for the candidate to have a PhD with at least 8 years of relevant research experience, preferably with 2-3 years of experience in an industry setting

Pay Rate: Depending on Experience

Industry: Clinical Stage Immuno-Oncology

Location: San Francisco Bay Area

Type: Direct Hire

Responsibilities
  • Develop in vitro, ex vivo and in vivo assay systems that interrogate both the function of myeloid cell populations and the activity of therapeutic molecules
  • Use murine tumor models and human tumor samples to understand the role of myeloid cells in sensitivity and resistance to therapeutic agents such as checkpoint inhibitors, chemotherapy, and/or radiotherapy
  • Closely collaborate with project and discovery teams to interrogate the mechanism-of-action of candidate antibodies targeting distinct myeloid subpopulations
  • Supervise and mentor junior staff members
  • Manage vendor and collaboration relationships
  • Contribute to the organizations research strategy by helping to expand the approaches used to target myeloid subpopulations within the tumor microenvironment
  • Support biomarker discovery efforts, including patient selection and stratification


Qualifications
  • PhD with at least 8 years of relevant research experience, preferably with 2-3 years of experience in an industry setting
  • Strong working knowledge of immuno-oncology and/or inflammation with emphasis on myeloid cells
  • Extensive knowledge of assays and systems for the interrogation of mouse and human immune cell function
  • Demonstrated experience with immune assays, including extensive experience with high-dimensional flow cytometry (14+ parameter) analysis of immune populations from blood, primary and secondary lymphoid tissues, and tumors
  • Experience planning, managing or conducting in vivo mouse syngeneic tumor studies (efficacy, pharmacodynamic, pharmacokinetic)
  • Expertise in myeloid biology as evidenced by authorship on high impact publications and patents
  • Experience with outsourcing and tech transfer of assays to third parties and CROs
  • Experience working in a fast-paced, cross-functional organization where collaboration is highly valued
  • Demonstrated ability to supervise and support career development of junior laboratory staff
  • Experience leading early drug development teams is a plus
  • Strong relationship-building and communication skills to empower teams and leverage strengths
  • Effective management of CROs and external partner collaborations
  • Excellent written and verbal communication skills, including preparation, organization, and synthesis of large amounts of data for presentation to internal and external audiences
You need to sign in or create an account to save a job.

Get job alerts

Create a job alert and receive personalized job recommendations straight to your inbox.

Create alert