Cell Line Development Biologist

Job Description

• Support the cell line development (CLD) team through participation in transfection, stable selection, cloning, expansion and characterization of mammalian cell lines for clinical and commercial production
• Perform laboratory experiments using a variety of CLD and cell culture technologies including single cell cloning/clone picking, cell imaging, liquid handling automation and Octet/ELISA-based recombinant protein quantification
• Support molecular characterization of the lead clonal cell lines for CLD programs including but not limited to mRNA analysis and gene copy number determination
• Works with departmental and/or cross functional peers to execute on assignments, under limited supervision.
• Prepares experimental protocols.
• Contributes significantly to project work which may include multiple projects within functional area.
• Interprets data independently, and contributes to technical reports
• Identifies technical issues, and implements solutions under supervision
• Contributes to the design of new applications/experiments/unit operations in consultation with supervisor.
• Coordinates within department as well as cross functionally with peers on projects.
  
  

Qualifications

• Bachelor's degree in biochemistry, biology, biotechnology, or related pharmaceutical science; 4+ years of biotechnology/biopharmaceutical industry experience in cell line development OR
• Master's degree in biochemistry, biology, biotechnology, or related pharmaceutical science; 1+ year of biotechnology/biopharmaceutical industry experience in cell line development
• Sound knowledge of cell culture principles, experience in aseptic techniques required
• Computer experience in common Microsoft applications (Word, Excel, PowerPoint) is required
• Experience in CLD technologies including culture of mammalian cells, single-cell cloning (sorting/clone picking), clonality assessment, and clone screening highly desirable
• Experience in molecular biology methods including subcloning, RT-qPCR/ddPCR and Octet/ELISA-based recombinant protein quantification is desirable
• Experience with FACS, automation or Next-Gen Sequencing will be a plus.
• Familiar with general laboratory procedures and aseptic technique.
• Able to troubleshoot critical issues or problems and resolve routine issues using appropriate information.
• Ability to work within department groups/team.
• Exercises good time management skills
• Proficiency in use of applicable lab equipment and operations; experience in maintaining written records of work in the form of laboratory notebooks (paper or electronic)
• Expresses one's self clearly and concisely within function; documents issues and/or concerns concisely with colleagues; timely and effectively communicates issues to supervisor
  
  

Additional Information

Position is full-time, Monday - Friday 8:00am - 5:00pm. Candidates currently living within a commutable distance of Cambridge, MA are encouraged to apply. Excellent full time benefits including comprehensive medical coverage, dental, and vision options

• Life and disability insurance
• 401(k) with company match
• Paid vacation and holidays
  
  

Eurofins is a M/F, Disabled, and Veteran Equal Employment Opportunity and Affirmative Action employer.