Research Associate

Description:

Responsibilities • Execute analytical test methods to support bioprocess development of AAV candidates. - Will be running HPLC so experience is required • Develop and qualify analytical methods to measure and monitor key quality attributes for AAV therapeutic materials. • Verify and pre-validate analytical test methods in preparation for method transfer to GMP CMO facilities. • Stay up-to-date on state-of-the-art methodologies for AAV characterization. • Write, prepare and present technical data, technical reports and standard operating procedures (SOPs) for internal use and transfer to external sites. • Work independently in a collaborative, scientifically stimulating, patient-focused research environment.

Skills:

hplc, chemistry, analytical chemistry, protein assays, AAV, Uv vis, assay development, assay, mass spectrometry, protein purification, chromatography, gel electrophoresis, capillary electrophoresis

Top Skills Details:

hplc,chemistry,analytical chemistry,protein assays

Additional Skills & Qualifications:

Requirements • BS or MS in Chemistry, Cell Biology, Biochemistry, or a related discipline with at least 2 years industry experience. - Potential Bio-Medical/Chemical Engineer as long as they've had protein + HPLC experience.. not med device types • Excellent problem-solving abilities for analyzing complex molecular entities. • HPLC/UPLC experience analyzing virus capsids, antibodies and/or other biologics materials by a variety of chromatographic methods (RP, SEC, IEX) and CE-based methods. • Knowledge on physicochemical characterization techniques, including but not limited to: AUC, MALS/DLS. • Managing contacts and communications with vendors, instrument services, software and instrument updates, and maintaining of the instruments. Including laboratory consumables related to the technical area. • Write, prepare, and present technical data, technical reports and standard operating procedures (SOPs) for internal use and transfer to external sites. • Proven ability to work independently and effectively plan and organize work activities and prioritize task completion to meet schedules and deadlines. • Strong collaborative work ethic and excellent time management skills for ongoing testing in parallel with new method development, in a fast-paced, scientifically rigorous, cross-functional team environment.

Experience Level:

Entry Level

About Actalent:

Actalent connects passion with purpose. Our scalable talent solutions and services capabilities drive value and results and provide the expertise to help our customers achieve more. Every day, our experts around the globe are making an impact. We're supporting critical initiatives in engineering and sciences that advance how companies serve the world. Actalent promotes consultant care and engagement through experiences that enable continuous development. Our people are the difference. Actalent is an operating company of Allegis Group, the global leader in talent solutions.

The company is an equal opportunity employer and will consider all applications without regards to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.