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Senior Scientist, Computational Biology

Employer
Scorpion Therapeutics
Location
San Francisco, California, US
Salary
Competitive
Closing date
Jan 15, 2022

View more

Sector
Consultancy/Private Sector
Field
Informatics / GIS
Discipline
Statistics, Biology
Salary Type
Salary
Employment Type
Full time
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Senior Scientist, Computational Biology

Scorpion Therapeutics

Scorpion Therapeutics is a precision oncology company founded in February 2020 by a preeminent group of scientists from Harvard University/Massachusetts General Hospital - Keith Flaherty, MD, Gaddy Getz, Ph.D. and Liron Bar-Peled, Ph.D. The company has raised $270M in Series A and Series B financings led by blue-chip investors, including Atlas Venture, Boxer Capital of Tavistock Group, EcoR1 Capital, LLC, Omega Funds, and Vida Venture.

Scorpion Therapeutics' mission is to serve oncology patients by discovering and developing best-in-class and first-in-class, small molecule cancer medicines that address large patient segments with significant unmet medical needs. To accomplish this mission, we are building a highly collaborative team focused on the pursuit of novel approaches to small molecule drug discovery. This approach relies upon dynamic collaboration between cancer biology, proteomics, informatics, structural biology and medicinal chemistry - with the ultimate goal of realizing the full potential of targeted/precision oncology.

We are seeking a highly motivated Computational Biologist to join our Data Science team in San Francisco, CA. This role will provide exposure to multiple phases of drug discovery and development, with a mission to leverage information-rich datasets to validate targets, elucidate mechanism of action, and inform patient selection strategy. The successful candidate will interface closely with colleagues across the company, and be a key contributor on a diverse, multidisciplinary team.

Key Responsibilities:
  • Identify and evaluate novel therapeutic targets through mining large -omics datasets
  • Analyze data from high-throughput molecular assays including RNA-seq, ChIP-seq, ATAC-seq and CRISPR screens
  • Work in close collaboration with scientists from target identification and validation group contributing to experimental design
  • Provide interpretation and analysis of results and present findings in cross-functional project team meetings
  • Maintain excellent communication across internal and external team members


Professional Experience/Qualifications:
  • Ph.D. in Computational Biology, Bioinformatics, Statistics, or other quantitative field plus 2 years of experience
  • Strong coding skills, fluency in using R or Python for complex data analysis
  • Experience in analysis of RNA-seq, WES and WGS data
  • Strong understanding of relevant concepts in cancer biology and molecular biology
  • Understanding of current best-practices for high-throughput genomics/molecular data analyses and their underlying statistical principles
  • Experience in network/pathway mapping and integration of orthogonal omics datasets
  • Experience with AWS compute environment is highly preferred
  • Experience with Nextflow DSL is a plus
  • Experience with R-Shiny/data visualization is a plus
  • A strong record of achievement, including publications in high-impact journals
  • Integrity, scientific rigor and commitment to teamwork


Scorpion Therapeutics Inc. is an Equal Opportunity Employer who strives to create and maintain a diverse working environment. We do not discriminate for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Beginning October 13, 2021, Scorpion requires all new hires to be fully vaccinated against COVID-19. If you are unable to receive the vaccine due to a disability or serious medical condition, or because of your sincerely held religious beliefs, you will have an opportunity to request a reasonable accommodation. Apply at: CAREERS@SCORPIONTX.COM
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