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Research Professional

Employer
University of Chicago
Location
The Loop, Illinois, US
Salary
Competitive
Closing date
Jan 15, 2022

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Sector
Academic / Research
Field
Conservation science
Discipline
Energy
Salary Type
Salary
Employment Type
Fellowship
Department BSD BMB - Research Staff: Perozo Lab About the Department The Department of Biochemistry and Molecular Biology studies how biomolecules operate and interact to drive the complex and diverse behaviors of living systems. Our research encompasses all areas of modern biochemistry, including structural biology, biophysics, biomolecular engineering and design, and evolution. As our interests continue to expand and adapt to new frontiers, we are looking for graduate students and postdoctoral fellows to join us in our pioneering work. Members of the department ask broad and multifaceted questions. As a result, our trainees are well equipped for future academic and industrial careers in biochemistry and biophysics. Job Summary The Perozo lab focuses on efforts to define the fundamental principles that drive the transduction of different forms energy (Electric field, Mechanical forces, ligand binding) into protein motion and it defines the function of excitable systems. The study of sensory membrane proteins falls squarely at the intersection of two of the lab's most important scientific questions: Voltage dependent conformational changes and mechanotransduction. Most membrane proteins have moving parts that help execute their specific function, often in response to an external stimulus. Our research aims to understand the molecular mechanisms underlying the transduction of different forms of energy defining the different molecular mechanisms of ion channel gating. We are equally interested in protein structure as in protein dynamics. Therefore, we rely on high resolution structural and spectroscopic methods to study channels and other membrane proteins embedded in a fluid lipid bilayer. Static structural analyses are pursued by X-ray crystallography. Responsibilities * Serves as a resource for collecting data and performing analysis. Contributes to facilitating and promoting a research project by providing scientific or intellectual information. * Reviews laboratory protocols and training on new techniques. Manage complex data sets for research. * Leads the contributions to scientific writing and publications, including protocols and grants. * Trains new laboratory personnel. * Performs other related work as needed. Minimum Qualifications Education: Minimum requirements include a PhD in related field. * -- Work Experience: Minimum requirements include knowledge and skills developed through 2-5 years of work experience in a related job discipline. * -- Certifications: * -- Preferred Qualifications Education: * PhD. Experience: * At least 2 years of post-doctorate experience. Preferred Competencies * Membrane protein biochemistry experience. * Sample prep and analyses of cryoEM single particle data (preference relion and cryospark) experience. * Skilled in patch clamp techniques (including bacterial spheroplast electrophysiology) experience. * Knowledge of molecular simulations using NAMD, or CHARMM experience. Working Conditions * Laboratory environment Application Documents * Resume (required) * Cover Letter ( preferred) When applying, the document(s) MUST be uploaded via the My Experience page, in the section titled Application Documents of the application. Job Family Research Role Impact Individual Contributor FLSA Status Exempt Pay Frequency Monthly Scheduled Weekly Hours 40 Benefits Eligible Yes Drug Test Required No Health Screen Required No Motor Vehicle Record Inquiry Required No Posting Statement Applicant Inquiry Form.Applicant Inquiry FormThe University of Chicago is an Affirmative Action/Equal Opportunity/Disabled/Veterans Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national or ethnic origin, age, status as an individual with a disability, protected veteran status, genetic information, or other protected classes under the law. For additional information please see the University's Notice of Nondiscrimination. Staff Job seekers in need of a reasonable accommodation to complete the application process should call 773-702-5800 or submit a request via Applicant Inquiry Form. We seek a diverse pool of applicants who wish to join an academic community that places the highest value on rigorous inquiry and encourages a diversity of perspectives, experiences, groups of individuals, and ideas to inform and stimulate intellectual challenge, engagement, and exchange. All offers of employment are contingent upon a background check that includes a review of conviction history. A conviction does not automatically preclude University employment. Rather, the University considers conviction information on a case-by-case basis and assesses the nature of the offense, the circumstances surrounding it, the proximity in time of the conviction, and its relevance to the position. The University of Chicago's Annual Security & Fire Safety Report (Report) provides information about University offices and programs that provide safety support, crime and fire statistics, emergency response and communications plans, and other policies and information. The Report can be accessed online at: http://securityreport.uchicago.edu. Paper copies of the Report are available, upon request, from the University of Chicago Police Department, 850 E. 61st Street, Chicago, IL 60637.

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