Scientist, Protein Purification

Yoh has an exciting opportunity for a Scientist, Protein Purification with expertise in process development that will directly support efforts to drive forward commercial offerings developing GMP processes in San Diego, CA. Our client is a well-funded, highly-buzz-about Biotech Startup, focused on developing targeted gene therapies for aging and age-related diseases. Reporting directly to the Sr. Director of Manufacturing, you would be responsible for independently developing and optimizing AAV production to enhance their clinical pipeline. Industry experience is NOT required, recent PhD graduates and Post Docs with experience developing and optimizing small & medium scale AAV production are encouraged to apply.

See below for complete job responsibilities and requirements. If after reviewing, you are interested in learning more about this, or other opportunities in Biotech, please apply with your updated resume ASAP.

Title: Scientist, Protein Purification
Salary: Competitive Salary
Location: San Diego, CA
Type: Full time, direct hire

Responsibilities:

• Setting, completing and updating milestones related to main project
• Performing cell culture (adherent and suspension) for virus creation and purification
• Developing and optimizing small and medium scale AAV production for scale up manufacturing
• Performing researching into ways of enhancing AAV production
• Participation in transfer and validation activities for upstream production to CDMO
• Performing standard and advanced cloning techniques
• Executing experiments, independently and in conjunction with a small team in support of research and clinical applications
• Following laboratory protocols and safety regulations
• Performing detailed and accurate documentation of all experiments and laboratory practices
• Accountable for on-time, high quality results and clearly communicating progress

Requirements:

• Ph.D. in virology, biology, biochemistry, microbiology, biomedical engineering, bioengineering or related field required
• Experience with AAV production or other biologic scale up production, protein interactions and FPLC are required.
• Demonstrated prior experience with AAV or biologic production and the pain points associated

Preferred experience:

• 2+ years of industry experience preferred.
• Experience with suspension cell culture and protein production
• Experience with flow cytometry, ELISAs, PCR, and microscopy
• Proven ability to draft and implement lab protocols.
• Experience with AAV production or other biologic scale up production, protein interactions and FPLC.

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