This job has expired

Scientist, Cell Therapy Process Development - R - 100736 - San Diego, CA

National Resilience
San Diego County, California, US
Closing date
Jan 15, 2022

View more

Academic / Research
Informatics / GIS, Development
Salary Type
Employment Type
Full time
You need to sign in or create an account to save a job.
Position Summary

This role will be responsible advancing Resilience R&D's knowledge of cell processing methods through innovative experimental design and efficient execution. The ideal candidate will have a proven track record in successfully developing new cell manufacturing techniques and reagents, working closely with a multidisciplinary team of scientists and engineers. They will be design and perform experiments using state-of-the-art approaches - integrating cutting edge technology, automation, and data science where appropriate. This role requires excellent communication and creativity, backed by a high level of velocity and rigor.

Job Responsibilities
  • Drive innovation through development of novel cell processing hardware and workflows to manufacture autologous cell therapies.
  • Design, execute, and interpret data from sophisticated experiments and clearly communicate key findings to teams within Resilience R&D.
  • Perform process characterization, optimization, and comparability studies, as required.
  • Perform practical beta-testing of new hardware and applications by adjacent technical teams.
  • Prepare and follow standard operating procedures, batch records, and other process documentation.
  • Analyze and document experimental data in electronic laboratory notebooks in a timely and accurate manner in accordance with the company quality management system.
  • Mentor research associates in proper laboratory techniques and scientific experimental design.
  • Attend and present scientific data to colleagues at internal meetings.
  • Participate in daily Agile stand-ups and weekly sprints with other members of the research team.

  • PhD degree in Biology, Engineering, Medicine or related discipline with 1-3 years of laboratory research or industry experience.
  • 3+ years of expertise in cell processing hardware and processes for T-cell, HSC, B, or other specific cell therapy manufacturing process.
  • Extensive hands-on experience in with commercial cell processing systems (Miltenyi Prodigy, Lonza Cocoon, Xuri Wave).
  • Demonstrated independent problem solving and systematic data-driven experimental design and execution.
  • Demonstrated ability to clearly communicate technical information and roadmaps through written protocols and/or presentations containing clean figures and visualizations.
  • Innovative and analytical thinker with outstanding interpersonal, communication, and leadership skill.
  • Must be highly disciplined and organized, self-motivated and enthusiastic about taking a hands-on approach to collaborative scientific discovery efforts.

Preferred Experience
  • Expertise in CRISPR and vector design and related annotation tools
  • Expertise in designing PCR and NGS assays for genome engineering
  • Statistical analysis of genotypic, gene expression data in bulk and single cell samples
  • Knowledge of viral vector design (AAV, Lentivirus, Gamma retrovirus) and vector manufacturing processes.
  • Experience in setting up and working within a GxP environment
  • Exposure to pre-clinical R&D and IND filing requirements for a cell and gene therapy products
  • Experience in interfacing with laboratory automation (e.g. automated liquid handlers) and data analysis software.
  • Experience with coding and running bioinformatics scripts (Python, numpy, scipy, pandas, jupyter).
PandoLogic. Keywords: Cell Biologist, Location: San Diego, CA - 92161
You need to sign in or create an account to save a job.

Get job alerts

Create a job alert and receive personalised job recommendations straight to your inbox.

Create alert