Head of Oncology Translational Research (OTR) Computational Biology.

Janssen Research & Development, L.L.C., a division of Johnson & Johnson's Family of Companies is recruiting for the Head of Oncology Translational Research (OTR) Computational Biology group which is to be located in Spring House, PA.

At the Janssen Pharmaceutical Companies of Johnson & Johnson, what matters most is helping people live full and healthy lives. We focus on treating, curing and preventing some of the most devastating and complex diseases of our time. And we pursue the most promising science, wherever it might be found.

Janssen Research & Development, LLC discovers and develops innovative medical solutions to address important unmet medical needs in oncology, immunology, neuroscience, infectious diseases and vaccines, and cardiovascular and metabolic diseases. Please visit http://www.janssenrnd.com/ for more information.

We are Janssen. Our mission drives us. Our patients inspire us. We collaborate with the world for the health of everyone in it.

Thriving on a diverse company culture, celebrating the uniqueness of our employees and committed to inclusion. Proud to be an equal opportunity employer.

The successful candidate will lead the Oncology Translational Research Computational Biology group, which is responsible for data analysis and Bioinformatics support for Oncology therapeutic development.

In This Role, You Will

• Lead a group of computational biologists and work in close collaboration with scientists in Discovery, Translational Medicine, Data Sciences and other important internal and external partners
• Identify and develop applications of bioinformatics and computational research to solve challenges in Translational Research and other areas of drug development
• Represent Translational Research as a leader in the Janssen R&D community by sharing vision and goals on key capabilities and projects.
• Analyze and integrate high dimensional data from a variety of platforms including next-generation sequencing, gene expression, SNP, RBM, and IHC
• Provide data analysis and statistical support to identify diseases mechanisms, mode of action for therapeutic interventions, and candidate biomarkers
• Oversee collaborations and contractor support
• Build, analyze, and interpret biological networks from disparate data sources
• Develop and communicate computational strategies and results in appropriate biological context, and present results to bench scientists, clinicians, and management
• Participate on multidisciplinary teams for discovery, preclinical and clinical development, biomarker and translational research
• Actively interface with the internal and external scientific and technical community, including the building of relationships in this community.
• Lead technology evaluations and software/database usage training
  
  

Qualifications

• A Ph.D., Bioinformatics, Computational Biology, or Biostatistics with 10+ years of relevant industry experience is required
• Stong background in cancer biology and cancer genetics research is required.
• Experience working and communicating with multidisciplinary teams in a fast paced environment is required.
• Proficient with statistical and biological data visualization software tools and methods (such as R/BioConductor) is required.
• In-depth knowledge of public and commercial biological databases (e.g. NCBI Entrez, NCBI GEO, UCSC Genome Browser, TCGA/caBIG, Oncomine, GeneGo, Ingenuity) is required.
• Self-motivated and proven effective leader of teams is required.
• Excellent presentation and oral/written communication skills is required.
• Demonstrated scientific excellence by a strong publication record and/or evidence of scientific initiative is required.
• Bioinformatics experience working with high dimensional data, gene expression analysis, survival analysis, and biological network reconstruction/inference is required.
• Statistical analysis experience with working knowledge of regression analysis, multivariate data analysis, and linear/nonlinear mixed effects modeling is required.
• Familiarity with classification and machine learning methods, and how they are applied to the life sciences is required.
• Strong working knowledge of software/code architecture, (e.g. R/BioConductor, Perl, Python) and how these languages are applied to address biologic problems is preferred.
• Comfortable working in Unix/Linux environment is preferred.
• Other high level programming (Java, C++, etc.) and database (e.g. MySQL, Postgres, Oracle) experience a plus.
• This position is to be located in Spring House, PA and may required up to 10% travel domestic or internationally.
  
  

Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

Primary Location

United States-Pennsylvania-Spring House-Welsh & McKean Roads

Organization

Janssen Research & Development, LLC (6084)

Job Function

R&D

Requisition ID

2105964802W