Tissue Culture and Molecular Biology Technician
- Employer
- Mirimus
- Location
- Brooklyn, New York, US
- Salary
- Competitive
- Closing date
- Dec 9, 2021
View more
- Sector
- Academic / Research
- Field
- Conservation science
- Discipline
- Modeling, Biology
- Salary Type
- Salary
- Employment Type
- Full time
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About Mirimus:
Mirimus specializes in developing tools for in vitro and in vivo research by harnessing the power of RNA interference (RNAi) and CRISPR/Cas genome editing for animal model creation and pre-clinical drug discovery pipeline development. Using the most advanced platforms of RNAi design for potent gene silencing and novel CRISPR/Cas gene editing approaches, for speedy animal modeling, Mirimus generates unique tools for large pharma drug discovery groups and CROs. Mirimus is partnered with Charles River Laboratory and performs all molecular biology and cell-based gene editing for CRL-North America. Our mission is to provide the most superior preclinical models for target discovery and therapeutics research in our combat against human health issues.
About the Role:
Mirimus is seeking highly motivated individuals to work with our model creation team to expand its capacity of Genetic Engineering Services. A suitable candidate should be an effective communicator, planning, prioritizing, and executing projects to meet commitments with a detail orientated mindset.
Job Responsibilities:
Successful candidates will be part of an innovative and creative team with the opportunity to apply their creativity to Mirimus' core vision.
Minimum Education and Experience Needed:
-BS in Biology, Molecular Biology, Genetics, Biotechnology, or related field
-Minimum 1 to 2 years of relevant research lab or industry experience
Qualifications:
- Must properly follow protocols, procedures, and instruction, attention to detail, work in a fast pace environment to meet deadlines, be eager to learn, and be able to work in a team and independently.
- Good record keeping skills
- Minimum 1-year experience with cell culture of mammalian cell lines.
- Knowledge to perform transfections of various cell lines.
- Experience handling ES cells, including analyzing and quantitating data from experiments is highly desired.
- Routinely performed molecular biology techniques such as genomic DNA extraction, PCR, plasmid mini-prep, and DNA sequence analysis.
- Good knowledge of scientific principles, methods and processes (technical and/or theoretical) used to conduct systematic and objective inquiry, methods of data collection and analyses, and interpreting and reporting results are required, as well as the ability to operate instruments and equipment and proficiency in related information technology including Microsoft Office, VectorNTI, SnapGene etc.
- Working knowledge of RNA interference, shRNA and/or siRNA, as well as gene editing techniques including homologous recombination and CRISPR/Cas9, and their applications to study gene function.
- Can effectively summarize and clearly report on a wide range of service line related tasks
- Must be able to operate lab instruments; must be familiar with MS Excel and computers.
- Excellent written and oral communication skills.
- Can interact with all individuals in productive ways to enhance Mirimus' goals and core vision.
- Shows respect and maintains a professional attitude to all lab members and outside collaborators.
Job Type: Full-time
Mirimus specializes in developing tools for in vitro and in vivo research by harnessing the power of RNA interference (RNAi) and CRISPR/Cas genome editing for animal model creation and pre-clinical drug discovery pipeline development. Using the most advanced platforms of RNAi design for potent gene silencing and novel CRISPR/Cas gene editing approaches, for speedy animal modeling, Mirimus generates unique tools for large pharma drug discovery groups and CROs. Mirimus is partnered with Charles River Laboratory and performs all molecular biology and cell-based gene editing for CRL-North America. Our mission is to provide the most superior preclinical models for target discovery and therapeutics research in our combat against human health issues.
About the Role:
Mirimus is seeking highly motivated individuals to work with our model creation team to expand its capacity of Genetic Engineering Services. A suitable candidate should be an effective communicator, planning, prioritizing, and executing projects to meet commitments with a detail orientated mindset.
Job Responsibilities:
- The job position will primarily work with the cell culture team on the validation and ES cell targeting process of our RNAi and CRISPR/Cas9 lines, as well as genotyping. They will also assist our Director of Embryology and cell culture/animal technician team with organization, timelines, and compiling data reports.
- In addition, the role will require working with specific projects or aspects imperative to our operational pipeline, working with the Genetic Engineering team on the targeting vector cloning, DNA sequence analysis, and vital upstream preparation for our validation and ES cell targeting team members. Projects will be based on our RNAi and CRISPR/Cas9 pipelines. Genotyping experience is a plus. The candidate will also assist our Director of Genetic Engineering Services and other molecular cloning team members with organization, timelines, and compiling data reports.
- Candidate will also have basic lab duties to prepare laboratory equipment, instruments, solutions, stains, assays and other supplies.
Successful candidates will be part of an innovative and creative team with the opportunity to apply their creativity to Mirimus' core vision.
Minimum Education and Experience Needed:
-BS in Biology, Molecular Biology, Genetics, Biotechnology, or related field
-Minimum 1 to 2 years of relevant research lab or industry experience
Qualifications:
- Must properly follow protocols, procedures, and instruction, attention to detail, work in a fast pace environment to meet deadlines, be eager to learn, and be able to work in a team and independently.
- Good record keeping skills
- Minimum 1-year experience with cell culture of mammalian cell lines.
- Knowledge to perform transfections of various cell lines.
- Experience handling ES cells, including analyzing and quantitating data from experiments is highly desired.
- Routinely performed molecular biology techniques such as genomic DNA extraction, PCR, plasmid mini-prep, and DNA sequence analysis.
- Good knowledge of scientific principles, methods and processes (technical and/or theoretical) used to conduct systematic and objective inquiry, methods of data collection and analyses, and interpreting and reporting results are required, as well as the ability to operate instruments and equipment and proficiency in related information technology including Microsoft Office, VectorNTI, SnapGene etc.
- Working knowledge of RNA interference, shRNA and/or siRNA, as well as gene editing techniques including homologous recombination and CRISPR/Cas9, and their applications to study gene function.
- Can effectively summarize and clearly report on a wide range of service line related tasks
- Must be able to operate lab instruments; must be familiar with MS Excel and computers.
- Excellent written and oral communication skills.
- Can interact with all individuals in productive ways to enhance Mirimus' goals and core vision.
- Shows respect and maintains a professional attitude to all lab members and outside collaborators.
Job Type: Full-time
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