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Associate Director, Liver Disease Biology

Intellia Therapeutics
Cambridge, Massachusetts, US
Closing date
Dec 9, 2021

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Academic / Research
Conservation science
Energy, Biology
Salary Type
Employment Type
Full time
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Intellia Careers Associate Director, Liver Disease Biology
Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases.

Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you can achieve more at Intellia. We have a single-minded determination to excel and succeed together. We believe in the power of curiosity and pushing boundaries. We welcome challenging thoughts and imagination to develop innovative solutions. And we know that patients are counting on us to make the promise a reality, so we must maintain high standards and get it done.

We want all of our people to go beyond what is possible. We aren't constrained by typical end rails, and we aren't out to just "treat" people. We're all in this for something more. We're driven to cure and motivated for change. Just imagine the possibilities of what we can do together.

How you will Achieve More with Intellia:

As an Associate Director, Liver Disease Biology, you will be joining a company where we are applying CRISPR/Cas9 genome editing and gene therapy technologies for therapeutic benefit. In your role as an Associate Director, you will oversee the advancement of our liver disease projects, bringing novel drug candidates with high potential for efficacy in humans into the early-stage pipeline. You will lead a team that generates key data for evaluating the mechanism of action and/or drug candidate efficacy and pharmacodynamics. Main responsibilities include:

Leading multiple cross-functional, disease-focused project teams from initiation to DC stage and onwards to IND

Directly supervising a team of amazing scientists working on novel applications of our hepatic genome editing platform

Overseeing the development of in vitro and in vivo assays to interrogate biological processes and test novel therapeutics

Delivering high-quality data to help advance drug discovery projects in the therapeutic portfolio

Generate new therapeutic hypotheses leveraging CRISPR/Cas9 gene editing

Proposing and developing innovative methodologies and technologies for project development

Presenting data to other scientific staff or cross-functional project team; may present data/posters to external research or scientific community

Acting as a scientific mentor and cultural ambassador within the company

About You:

Are you a scientific leader with strong management experience and deep subject-matter expertise in liver disease biology? Candidates interested in applying should have a PhD in Cell Biology, Biochemistry, or a related field. The ideal candidate will also have experience in drug discovery or target validation research. If you consider yourself a strong communicator and enjoy managing a team, we encourage you to apply! Other qualifications include:

Experience leading a diverse project team to successfully achieve objectives under tight timelines and with rapidly changing priorities

Deep knowledge of inherited diseases of the liver and relevant animal models of liver disease Bioassay development, optimization, and validation

Experience with CRISPR/Cas9 technology

Meet your future team:

The Disease Biology team is a group of bright, fun, and team-first individuals. Your future hiring manager is the Vice President, Disease Biology. Having spent nearly 6 years with Intellia, the hiring manager is very knowledgeable on the company's history and mission. Your future team is a group of dedicated individuals, driven to change patients' lives. As we build our team, we're excited to work with people who share our commitment and energy to making a difference.

The team is currently working mostly onsite. Therefore, we hope you are currently local to Cambridge, MA, or that you are open to relocating. While much of the day-to-day operations require wet-lab work, our team is focused on building not just technical expertise but fostering an environment for the growth of scientists interested in a career in therapeutic biotechnology. If you join our team, you can expect to join a fast, exciting, and collaborative environment. We look forward to fostering your skills, learning from your experiences, and building a larger team together.


Covid-19 Vaccination Policy: Effective Monday, January 3, 2022, all Intellia employees, regardless of work location, must be fully vaccinated for COVID-19. Requests for exemption for medical or sincerely held religious beliefs will be considered.

EEOC Statement: Intellia believes in a diverse environment, and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Intellia will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

At Intellia, we are committed to solving the complex challenges of making CRISPR/Cas9-based medicines a reality for patients suffering from genetic diseases and to create novel engineered cell therapies for immuno-oncological and autoimmune diseases.
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