Principal Research Scientist-Nucleic Acid Biology

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.

We serve an extraordinary purpose. For more than 140 years, we have worked diligently to discover medicines that make life better. These discoveries start in Lilly Research Laboratories, where our scientists work to create new medicines that will help solve our world's greatest health challenges.

At the Lilly Innovation Center in Cambridge, Massachusetts, we explore how next generation therapeutics, new technologies, data analytics and new care models can improve patient health and the healthcare system. Our team, the Novel Therapeutic Modalities (NTM), in Cambridge shares a real passion for challenging conventional wisdom and creating an environment that embraces creative, break-through concepts. The Center offers a start-up environment with large company support. It is located in the heart of Massachusetts' exploding science and technology cluster and is within walking distance of some of the best academic and industry innovators in the world.

The successful candidate will have a strong research track record in biology (wet lab and/or computational) and be analytically-minded, systematic, and embrace data-driven decision making. The scientist will collaborate with a multidisciplinary team to perform experiments to aid development of RNA oligomer drug candidates for the next generation of RNA therapies.

Key responsibilities include:
Recruit, hire, train and supervise a team of nucleic acid biologists, biochemists, and/or biophysicistsEvaluate novel nucleic acid modalities (e.g., gene editing and/or therapy, RNA editing, saRNA, ASOs) using cell and molecular biology techniques (transfection or electroporation of various cell lines and primary cells, qPCR, Western blot, sequencing, luminescence-based assays).Visualize, summarize, and present results to team membersContribute to scientific projects where solutions are developed through interactions with diverse talent across the larger organization.Identify and drive solutions toward innovation in the RNA Therapeutics areaDemonstrate high learning agility regarding grasping and exploiting new scientific concepts and methods across multiple teams.Partner with cross-functional partners to drive high-speed innovationEmbrace diversity of thought, background and experience to deliver innovative solutions.Possess strong communication (oral, written), organizational, and leadership skills.

Basic Qualifications:
Ph.D. in biology or other scientific area with at least 5 years of post-PhD/post training (i.e. postdoctoral) experience, particularly practical experience with cell biology and cell imaging.

Additional Skills/Preferences :
The ideal candidate will possess a solid understanding of RNA biology and RNA therapeutics.Demonstrated track record for publication and presentation of research results.Previous management experienceGood interpersonal skills and a sustained tendency for collaborationDemonstrated initiative and appropriate risk-takingDemonstrated technical proficiency and ability to create ideas for future work plansStrong technical skills to supply business valueKnowledge and experience with management of a technical projectAbility to prioritize multiple activities and manage ambiguity

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

As a condition of employment with Eli Lilly and Company and its subsidiaries in the United States and Puerto Rico, you must be fully COVID-19 vaccinated and provide proof of vaccination satisfactory to the company. If you would like to request an accommodation for medical or religious reasons, you may do so at workplace_adjustment@lilly.com.