Overview We are currently searching for an Animal Biologist to support the research in a molecular and systems neuroscience laboratory by assisting in work with genetically modified mice. This opportunity is full-time, and it is on site in Bethesda, MD. Duties & Responsibilities * Document all laboratory procedures, experiments and results; maintain and update laboratory notebooks and databases * Manage oversight and progress of critical results in animal-based experiments including evaluating goal-specific phenotypes of animals; collaborate with Primary investigators and other experimental team members to determine, evaluate and discuss the progress of projects * Work with staff on the modification of laboratory protocols and experiments based on literature findings * Develop, validate, perform and interpret a variety of complex experimental techniques and procedures; work with staff to develop procedures addressing new animal study needs, logistics, modifications to standard operating procedures, andor existing guidelines to resolve technical problems * Update and maintain laboratory notebooks and databases; collect, analyze and interpret data * Coordinate husbandry, animal care and enrichment activities to maintain a clean, safe and regulatory compliant animal research program * Work with staff to maintain, breed, genotype and phenotype transgenic animal colony; maintain records of animal colony * Develop and maintain a spreadsheet of animal breeding records; record lineage, genotype, birth, death and experimental use of each animal * Set up animals to be available in numbers and at the time required * Develop and maintain a breeding database to record all animals in the breeding colony * Anticipate animal needs for lab research and colony maintenance; adjust the number of breeding pairs accordingly * Communicate and collaborate with investigators regarding colony and support duties * Handle, dissect and euthanize animals * Maintain animal colony, including general husbandry, breeding, plug checks, weaning, tagging animals and obtaining tail or ear snips for genotyping, and euthanasia * Perform animal surgeries, including utero electroporation * Handle, dissect and euthanize animals * Perform skilled routine surgical procedures in support of on-going animal studies * Harvest and collect animal embryos, tissues, and organs * Perform a variety of specialized tissue fixation, embedding, sectioning and staining techniques * Manage genotyping of samples of transgenic animals * Perform analysis of animal tissues; prepare frozen slices and paraffin sections, appropriately stained to demonstrate normal and abnormal structures * Perform a variety of specialized tissue fixation, embedding, sectioning and staining techniques * Perform light and confocal microscopy * Work with staff to process tissue for immunohistochemistry * Maintain records of experimental results; work with staff to analyze and interpret data; prepare summaries of laboratory findings * Document information on procedures, modifications and methods for input into final publication and presentations of findings at meetings # SOAR #LI-SK1 Requirements Skills * Basic animal (mouse) husbandry * Tissue harvesting and processing * immunohistochemistry * survival surgery Qualifications * Bachelor's degree in a biological field (Neuroscience, Molecular Biology, Genetics) * At least 1-2 years of experience * Due to our contractual requirements and federal orders, including an Executive Order from the White House and an emergency regulation from the Centers for Medicare & Medicaid Services (CMS), the position for which you are applying requires that you provide proof of your vaccination status. If you are unable to receive the COVID-19 vaccine for medical reasons or because of a sincerely held religious belief, you may request an exemption from the vaccination requirement which shall be reviewed after the submission of requested documentation. If an accommodation is granted, the conditions may include weekly testing and masking. All Guidehouse employees also agree to follow any additional health and safety mitigation policies that may be required in the workplace. Company Description We are a trusted government partner that blends deep domain expertise with advanced technologies to help our customers solve complex problems that improve, protect, and save lives. As a rapidly growing company, we combine entrepreneurial spirit, customer focus, and an outcomes-based approach to support agency missions in health IT, life sciences, public safety, and grants management. The Dovel Family of Companies offers employees an opportunity to advance beyond a specific role or contract, we offer a path to develop an enriching career. We believe in empowering a culture of innovation, customer success, and employee growth. What you'll get… * Time Off! Flexible schedules and company paid holidays allow you to take the time you need. * Investment in YOU! 401(K) company contributions are yours to keep with no waiting period. * Choices! Unique healthcare plans to choose from with options like fertility and orthodontia benefits. * Discovery! With our tuition assistance and training programs, we support your career advancement. * Tax Savings! Enroll in pre-tax Health or Dependent Care Flexible Spending, HSA with company contributions, parking, and/or transit commuter benefits. * Support! Working parents and busy professionals - we've got you covered with a supportive culture, confidential Employee Assistance Program and a membership to Care.com. * Perks! Employee discounts, peer recognition programs, company-wide wellness challenges, and fun community events. * A Voice! A unique culture where you can influence decisions and have your voice heard. We are an Equal Opportunity Employer with a commitment to diversity. All individuals, regardless of personal characteristics, are encouraged to apply. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, sexual orientation, gender identity, disability, or veteran status.