Biology Research Scientist

POSITION: Research Scientist - Assay Development and Screening

Would you like to discover next-generation medicines? At Rgenta Therapeutics, we unlock the therapeutic potentials of targets that are highly disease-relevant but undruggable by traditional protein-targeting approaches. We have built proprietary RNA-targeting platforms that leverage our deep knowledge and innovative ideas in data-driven genomics, computational biology, high-throughput screening, and medicinal chemistry. We are a vibrant and exciting venture-backed startup located in the Greater Boston area. Developing new medicines demands a team of individuals with scientific curiosity, a can-do attitude, passion for progress, complementary skills, and thinking outside the box. Join Rgenta to discover new medicines and make scientific breakthroughs!

ROLE RESPONSIBILITIES:

• Design, develop, and optimize novel biochemistry and cell-based assays for lead discovery and optimization
• Develop and maintain state-of-the-art automation workflow for high-throughput screening and hit confirmation
• Design and execute molecular biology, cell biology, and genomics experiment to support target discovery and validation
• Responsible for screening data acquisition, tracking, and processing

BASIC QUALIFICATIONS:

• MS or PhD degree in Biology or Pharmacology, or equivalent industrial experience
• Minimum 2-5 years of relevant research experience in the academic or pharmaceutical industry
• Broad experience with molecular and cell biology experimental techniques (e.g. RT-PCR, qPCR, Western, ELISA, siRNA, shRNA, CRISPR)
• Experience with cell based or biochemical assays is desirable
• Experience in developing plate-based HTS assays and automation workflow is desirable
• Experience with NGS-based genomic profiling techniques such as RNA-seq, ChIP-seq, Amplicon-seq is a plus
• Demonstrated learning agility and success moving into and mastering new or unfamiliar areas of science

EEO & Employment Eligibility: Rgenta Therapeutics is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Rgenta Therapeutics also complies with all applicable federal, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Rgenta Therapeutics is an E-Verify employer.