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Executive Director, Biology

Alameda County, California, US
Closing date
Oct 27, 2021

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Company Description

Every Exelixis employee is united in an ambitious cause: to launch innovative medicines that give patients and their families hope for the future. In this pursuit, we know our employees are our most valuable asset. After operating in the challenging biotech sector for 25 years, we have a proven track record of resiliency in the face of adversity. The success of our lead product has provided a solid commercial foundation allowing us to reinvigorate our research efforts, and grow our team in areas such as Drug Discovery, Clinical Development and Commercial.

As we expand our global partnerships and further reinvest in R&D to help us discover the next breakthrough for difficult-to-treat cancers, we're seeking to add talented, dedicated employees to power our mission.

Cancer is our cause. Make it yours, too.

Job Description

As a member of the biotherapeutics group, the incumbent plays a key role in supporting the efforts for advancing the antibodies, ADCs and bispecifics portfolio at Exelixis. The incumbent supports the head of biotherapeutics in understanding mechanism of action and leads research activities of ongoing and new projects. Leads one or more biologics projects in the research pipeline.


  • Leadership and execution of antibody-based therapeutic programs.
  • Interact and collaborate with other biotherapeutics department team members, internal departments in development (pharmacokinetics, toxicology, translational medicine, pharmaceutical development) and external collaboration colleagues to discuss and resolve project needs and issues in research and early development of biotherapeutics.
  • Project lead in collaboration with scientific research and development. Participates in cross-functional team to implement research plans.
  • Identify and manage critical path activities and resources for development candidate nomination.
  • Identify and manage interdependencies and hand-offs.
  • Identify and proactively mitigate roadblocks.
  • Lead and manage projects in external collaborations
  • Provide support in evaluation of biologics research platforms and preclinical licensing candidates as needed.
  • Maintain consistent, multi-level communication with Development Team Members, Senior Management, and the Executive Team.
  • Work on external collaborations.
  • Follow company intellectual property and compliance policies and practices.
  • Comply with company health and safety policies and general laboratory practices.
  • Departmental activities such as budget planning, administrative management and employee performance development and planning if position oversees internal employees.
Supervisory Responsibilities
  • Directly supervises employee(s)

  • Doctoral degree (Ph.D.) in related scientific discipline such as biology, immunology, biochemistry, molecular biology or microbiology and a minimum of fourteen years of experience in the biotechnology/pharmaceutical industry post Ph.D.
  • Equivalent combination of education and experience
  • Strong background in biologics domain. Experience with ADCs is a must
  • Experience leading and managing Oncology/ ADC/Immuno-Oncology Programs
  • Research experience with antibody-based therapeutics from discovery to IND
  • Experience writing intellectual property filings, reports, and non-clinical IND sections
  • Extensive scientific knowledge in field biologics in Oncology and experience taking biologics projects from discovery to IND
  • Extensive knowledge of in vitro and in vivo characterization and translational pharmacology of ADCs and bispecifics
  • Knowledge of intellectual property matters, and issues related to biotherapeutics.
  • The knowledge to apply advanced scientific and technical principles, theories, and concepts, and contribute to the development of new principles and concepts.
  • Ability to set goals with an understanding of priority and impact to program, department, and organization.
  • Think strategically and solution oriented.
  • Take a hands-on, "roll up your sleeves" approach.
  • Ability to drive, facilitate, track, anticipate, influence, and implement team objectives; challenge the status quo where relevant.
  • Ability to resolve conflicts within the team
Job Complexity
  • Works on extremely complex problems where analysis of situations or data requires an evaluation of intangible variables.
  • Exercises independent judgment in developing methods, techniques, and evaluation criteria for obtaining results.
  • Uses professional concepts to contribute to development of company concepts and principles and to achieve objectives in creative and effective ways.
Additional Information


The preceding job description has been designed to indicate the general nature and level of work performed by employees within this classification. It is not designed to contain or be interpreted as a comprehensive inventory of all duties, responsibilities and qualifications required of employees assigned to the job.

We are an Equal Opportunity Employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity, status as a veteran, and basis of disability or any other federal, state or local protected class.
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