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Principal Scientist, Translational Biology

Commonwealth Sciences Inc.
North Quincy, Massachusetts, US
Closing date
Oct 23, 2021

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Position located in Cambridge, MA.

Responsibilities of the Principal Scientist, Translational Biology:
  • Identify rationales for combination therapies and investigate mechanisms of resistance.
  • Using data from preclinical and human samples to identify biomarkers in patient samples including predictive, prognostic, diagnostic, pharmacodynamic, pharmacokinetic and others.
  • Responsible for biomarker assays from conception and development to transferring, validation and monitoring at external labs.
  • Provide translational strategies, data and tools to program teams.
  • Organize and manage human and non-human tissue samples.
  • Seek and establish contract with CRO, vendors and external collaborators to advance programs.
  • Help create and setup translational infrastructure and workflow.

Requirements of the Principal Scientist, Translational Biology:
  • PhD with 5+ years or M.S. with 10+ years of industry experience.
  • Worked with biomarkers in immuno-oncology or immunology in the biopharmaceutical setting.
  • Implemented biomarker strategies into working assays at central labs, including analysis and interpretation of downstream data.
  • Expertise in one of the following disciplines pathology, bioinformatics, genomics.
  • Experience working with human tissue and familiarity with tracking requirement.

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