Postdoctoral Associate training opportunities are immediately available within the Advanced Center for Translational Genetic Medicine (ACT-GeM) within the Stanley Manne Children's Research Institute. Candidates will be considered for a wide range of interdisciplinary projects with readily available funding. The ideal candidates will be accomplished, highly motivated, and creative scientists with interests in at least one of the three following areas: 1) understanding the architecture of human genetic disease; 2) investigating the mechanisms underlying disease processes; and 3) identification of novel therapeutic paradigms for inherited disorders. Candidates will have the opportunity to work with unique pediatric cohorts; cell-based, zebrafish and/or mouse models; and cutting-edge molecular and imaging technologies in a state-of-the-art facility. The ultimate goal is for postdoctoral fellows to gain training that will help to launch their careers as independent investigators.
Research topics can be chosen based on the interests and background of the individual candidate. Potential projects include, but are not limited to the following research themes:
Genetic and functional investigation of rare structural birth defects.
Functional study of genes that cause pleiotropic phenotypes.
Cis complementation and phenotype modifier phenomena in ciliopathies.
Dissection of copy number variants in neuroanatomical traits.
Mechanistic study of inherited kidney disorders affecting renal structure or function.
Therapeutic target discovery in rare pediatric disorders.
Design and implement research protocols; design safety procedures; adapt new procedures, methods or instrumentation relative to research procedures.
Collect, prepare and analyze research data; keep detailed written or electronic records summarizing experiments and recording of research data; use graphics and statistical software to analyze and present data.
Supervise other personnel in the laboratory to coordinate research efforts for increased efficiency; participate in training of fellows, residents, students and volunteer workers as needed.
Search pertinent scientific literature and draft/edit manuscripts.
Assist the PI with grant writing and apply for applicable fellowship opportunities.
Present data in written and oral form at local and national meetings.
Perform other job functions as assigned.
PhD. in a basic or health science. MD or DDS also acceptable. 0 - 2 years of experience.
Previous experience in genetics; cell, molecular, or computational biology; botany; zoology or other directly related scientific fields are desirable but not required.
Excellent written and oral communication skills, with demonstrated competency in the English language.
Ability to work in a highly collaborative fast-paced environment.
Ability to successfully interact with diverse stakeholders including: clinicians, basic scientists, and
Ability to multitask and manage multiple ongoing projects simultaneously.
Ability to work independently and as part of a team.